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An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer.
(PLoS One, 2008-04-02)
BACKGROUND: A major challenge in oncology is the selection of the most effective chemotherapeutic
agents for individual patients, while the administration of ineffective chemotherapy
increases mortality and decreases quality ...
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.
(PLoS One, 2008-01-02)
PURPOSE: To define the biology driving the aggressive nature of breast cancer arising
in young women. EXPERIMENTAL DESIGN: Among 784 patients with early stage breast cancer,
using prospectively-defined, age-specific cohorts ...