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Now showing items 111-117 of 117
Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.
(Lab Invest, 2010-12)
Hedgehog (Hh) pathway activation promotes many processes that occur during fibrogenic
liver repair. Whether the Hh pathway modulates the outcomes of virally mediated liver
injury has never been examined. Gene-profiling studies ...
Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system.
(BMC Health Serv Res, 2011-10-11)
BACKGROUND: The CDC's Family History Public Health Initiative encourages adoption
and increase awareness of family health history. To meet these goals and develop a
personalized medicine implementation science research agenda, ...
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.
(Circ Cardiovasc Genet, 2010-04)
BACKGROUND: Molecular tools may provide insight into cardiovascular risk. We assessed
whether metabolites discriminate coronary artery disease (CAD) and predict risk of
cardiovascular events. METHODS AND RESULTS: We performed ...
Establishment of normative ranges of the healthy human immune system with comprehensive polychromatic flow cytometry profiling.
(PloS one, 2019-01)
Existing normative flow cytometry data have several limitations including small sample
sizes, incompletely described study populations, variable flow cytometry methodology,
and limited depth for defining lymphocyte ...
Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.
(J Hematol Oncol, 2018-03-04)
BACKGROUND: The binding of CXCR4 with its ligand (stromal-derived factor-1) maintains
hematopoietic stem/progenitor cells (HSPCs) in a quiescent state. We hypothesized
that blocking CXCR4/SDF-1 interaction after hematopoietic ...
The accuracy and completeness for receipt of colorectal cancer care using Veterans Health Administration administrative data.
(BMC Health Serv Res, 2016-02-11)
BACKGROUND: The National Comprehensive Cancer Network and the American Society of
Clinical Oncology have established guidelines for the treatment and surveillance of
colorectal cancer (CRC), respectively. Considering these ...
Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component.
(The American journal of surgical pathology, 2011-02)
The normal counterparts of mantle cell lymphoma (MCL) are naive, quiescent B cells
that have not been processed through the germinal center (GC). For this reason, although
lymphomas arising from GC or post-GC B cells often ...