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Now showing items 21-30 of 42
Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254).
(Arthritis Res Ther, 2010)
INTRODUCTION: Acute trauma involving the anterior cruciate ligament is believed to
be a major risk factor for the development of post-traumatic osteoarthritis 10 to
20 years post-injury. In this study, to better understand ...
Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations.
(Ann Rheum Dis, 2010-05)
BACKGROUND: A lack of biomarkers that identify patients at risk for severe osteoarthritis
(OA) complicates development of disease-modifying OA drugs. OBJECTIVE: To determine
whether inflammatory genetic markers could stratify ...
Predicting virologic failure among HIV-1-infected children receiving antiretroviral therapy in Tanzania: a cross-sectional study.
(J Acquir Immune Defic Syndr, 2010-08)
BACKGROUND: Many HIV care and treatment programs in resource-limited settings rely
on clinical and immunologic monitoring of antiretroviral therapy (ART), but accuracy
of this strategy to detect virologic failure (VF) among ...
Rationale and design of the Exercise Intensity Trial (EXCITE): A randomized trial comparing the effects of moderate versus moderate to high-intensity aerobic training in women with operable breast cancer.
(BMC Cancer, 2010-10-06)
BACKGROUND: The Exercise Intensity Trial (EXcITe) is a randomized trial to compare
the efficacy of supervised moderate-intensity aerobic training to moderate to high-intensity
aerobic training, relative to attention control, ...
Cryptococcal cell morphology affects host cell interactions and pathogenicity.
(PLoS Pathog, 2010-06-17)
Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size
of cryptococcal cells is typically 5 to 10 microm. Cell enlargement was observed in
vivo, producing cells up to 100 microm. These morphological ...
Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States.
(PLoS Pathog, 2010-04-22)
Cryptococcus gattii causes life-threatening disease in otherwise healthy hosts and
to a lesser extent in immunocompromised hosts. The highest incidence for this disease
is on Vancouver Island, Canada, where an outbreak is ...
Similar T-cell immune responses induced by group M consensus env immunogens with wild-type or minimum consensus variable regions.
(AIDS Res Hum Retroviruses, 2010-05)
Consensus HIV-1 genes can decrease the genetic distances between candidate immunogens
and field virus strains. To ensure the functionality and optimal presentation of immunologic
epitopes, we generated two group-M consensus ...
Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles.
(PLoS One, 2010-07-12)
In the event of a terrorist-mediated attack in the United States using radiological
or improvised nuclear weapons, it is expected that hundreds of thousands of people
could be exposed to life-threatening levels of ionizing ...
Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts.
(PLoS One, 2010-07-12)
Stem cell transplantation holds great promise for the treatment of myocardial infarction
injury. We recently described the embryonic stem cell-derived cardiac progenitor cells
(CPCs) capable of differentiating into ...
Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus.
(BMC Genomics, 2010-02-18)
BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally
regulate gene expression in a variety of organisms, including insects, vertebrates,
and plants. miRNAs play important roles in cell development ...