Search
Now showing items 21-30 of 315
Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival.
(Carcinogenesis, 2018-07)
Prostate cancer (PCa) is a clinically and molecularly heterogeneous disease, with
variation in outcomes only partially predicted by grade and stage. Additional tools
to distinguish indolent from aggressive disease are needed. ...
Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival.
(Molecular carcinogenesis, 2018-01)
Metzincins are key molecules in the degradation of the extracellular matrix and play
an important role in cellular processes such as cell migration, adhesion, and cell
fusion of malignant tumors, including cutaneous melanoma ...
"I Use Weed for My ADHD": A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD.
(PLoS One, 2016)
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a risk factor for problematic
cannabis use. However, clinical and anecdotal evidence suggest an increasingly popular
perception that cannabis is therapeutic ...
Recovery and survival from aging-associated diseases.
(Exp Gerontol, 2013-08)
OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan
of the US elderly population may lead to erroneous conclusions when recovery/long-term
remission factors are underestimated. Using two ...
Steps to Health employee weight management randomized control trial: short-term follow-up results.
(J Occup Environ Med, 2015-02)
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study,
a randomized trial to evaluate the effectiveness of two employee weight management
programs offered within Duke University and the Health ...
Leukocyte telomere length, breast cancer risk in the offspring: the relations with father's age at birth.
(Mech Ageing Dev, 2011-04)
Recent studies have reported that leukocyte telomere length (LTL) is longer in offspring
of older fathers. Longer telomeres might increase cancer risk. We examined the relation
of father's age at the birth of the offspring ...
Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells.
(Chromosome Res, 2011-05)
Human centromeres contain multi-megabase-sized arrays of alpha satellite DNA, a family
of satellite DNA repeats based on a tandemly arranged 171 bp monomer. The centromere-specific
histone protein CENP-A is assembled on ...
Does surgery improve outcomes for esophageal squamous cell carcinoma? An analysis using the surveillance epidemiology and end results registry from 1998 to 2008.
(J Am Coll Surg, 2012-11)
BACKGROUND: We examined survival associated with locally advanced esophageal squamous
cell cancer (SCC) to evaluate if treatment without surgery could be considered adequate.
STUDY DESIGN: Patients in the Surveillance, ...
Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci.
(Kidney Int, 2015-10)
Acute kidney injury (AKI) is a common, serious complication of cardiac surgery. Since
prior studies have supported a genetic basis for postoperative AKI, we conducted a
genome-wide association study (GWAS) for AKI following ...
Randomized trial on mindfulness training for smokers targeted to a disadvantaged population.
(Subst Use Misuse, 2014-04)
We report the results of a randomized trial comparing a novel smoking cessation treatment
Mindfulness Training for Smokers (MTS) to a usual care therapy (Controls), which included
the availability of a tobacco quit line ...