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Now showing items 21-30 of 103
Impact of increases in high-density lipoprotein cholesterol on cardiovascular outcomes during the armed forces regression study.
(J Cardiovasc Pharmacol Ther, 2010-12)
INTRODUCTION: high-density lipoprotein (HDL) cholesterol is a well-established inverse
risk factor for cardiovascular disease. The extent to which cardiovascular risk can
be modified through changes in HDL, however, is less ...
Patterns of care quality and prognosis among hospitalized ischemic stroke patients with chronic kidney disease.
(J Am Heart Assoc, 2014-06-05)
BACKGROUND: Relatively little is known about the quality of care and outcomes for
hospitalized ischemic stroke patients with chronic kidney disease (CKD). We examined
quality of care and in-hospital prognoses among patients ...
Contemporary trends and predictors of postacute service use and routine discharge home after stroke.
(J Am Heart Assoc, 2015-02-23)
BACKGROUND: Returning home after the hospital is a primary aim for healthcare; however,
additional postacute care (PAC) services are sometimes necessary for returning stroke
patients to their pre-event status. Recent trends ...
The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.
(Eur Heart J, 2015-12-07)
BACKGROUND: Therapeutic decisions in atrial fibrillation (AF) are often influenced
by assessment of bleeding risk. However, existing bleeding risk scores have limitations.
OBJECTIVES: We sought to develop and validate a ...
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
(PLoS One, 2012)
OBJECTIVES: To determine if caloric restriction (CR) would cause changes in plasma
metabolic intermediates in response to a mixed meal, suggestive of changes in the
capacity to adapt fuel oxidation to fuel availability or ...
Pilot study of myocardial ischemia-induced metabolomic changes in emergency department patients undergoing stress testing.
(PloS one, 2019-01)
BACKGROUND:The heart is a metabolically active organ, and plasma acylcarnitines are
associated with long-term risk for myocardial infarction. We hypothesized that myocardial
ischemia from cardiac stress testing will produce ...
A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls.
(Arthritis Res Ther, 2016-04-12)
BACKGROUND: RA and CVD both have inflammation as part of the underlying biology. Our
objective was to explore the relationships of GlycA, a measure of glycosylated acute
phase proteins, with inflammation and cardiometabolic ...
Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.
(Journal of the American Heart Association, 2016-11-04)
The relationship between "on-treatment" low platelet reactivity and longitudinal risks
of major bleeding dual antiplatelet therapy following acute coronary syndromes remains
uncertain, especially for patients who do not ...
Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans.
(J Infect Dis, 2016-05-01)
BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is a globally prevalent cause
of diarrhea. Though usually self-limited, it can be severe and debilitating. Little
is known about the host transcriptional response to infection. ...
Benefit of Ezetimibe Added to Simvastatin in Reduced Kidney Function.
(J Am Soc Nephrol, 2017-10)
Efficacy of statin-based therapies in reducing cardiovascular mortality in individuals
with CKD seems to diminish as eGFR declines. The strongest evidence supporting the
cardiovascular benefit of statins in individuals with ...