Now showing items 31-40 of 173
Collagen biomarkers for arthritis applications.
(Biomark Insights, 2007-02-07)
A new instrument for measuring anticoagulation-related quality of life: development and preliminary validation.
(Health Qual Life Outcomes, 2004-05-06)
BACKGROUND: Anticoagulation can reduce quality of life, and different models of anticoagulation management might have different impacts on satisfaction with this component of medical care. Yet, to our knowledge, there are ...
Identification and utilization of arbitrary correlations in models of recombination signal sequences.
(Genome Biol, 2002)
BACKGROUND: A significant challenge in bioinformatics is to develop methods for detecting and modeling patterns in variable DNA sequence sites, such as protein-binding sites in regulatory DNA. Current approaches sometimes ...
Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages.
(Arthritis Res Ther, 2009)
INTRODUCTION: Certain amino acids within proteins have been reported to change from the L form to the D form over time. This process is known as racemization and is most likely to occur in long-lived low-turnover tissues ...
Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: a systematic review and meta-analysis.
(Br J Cancer, 2008-01-29)
The aim of this study was to determine the efficacy of palliative oxygen for relief of dyspnoea in cancer patients. MEDLINE and EMBASE were searched for randomised controlled trials, comparing oxygen and medical air in cancer ...
Patient detection of a drug dispensing error by use of physician-provided drug samples.
Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced.
(J Exp Med, 2002-05-06)
To understand the relationship between the affinity of the B cell antigen receptor (BCR) and the immune response to antigen, two lines of immunoglobulin H chain transgenic (Tg) mice were created. H50Gmu(a) and T1(V23)mu(a) ...
Measuring disease-free survival and cancer relapse using Medicare claims from CALGB breast cancer trial participants (companion to 9344).
(J Natl Cancer Inst, 2006-09-20)
To determine the accuracy with which Medicare claims data measure disease-free survival in elderly Medicare beneficiaries with cancer, we performed a criterion validation study. We merged gold-standard clinical trial data ...
Serum C-Reactive Protein (CRP), Target for Therapy or Trouble?
(Biomark Insights, 2007-02-07)
High sensitivity serum C-reactive protein (hs-CRP) has come into clinical use as a marker of risk for cardiovascular disease (CVD). In addition to a role as a marker of disease, CRP has also been implicated in the pathogenesis ...
Comorbidity, age, race and stage at diagnosis in colorectal cancer: a retrospective, parallel analysis of two health systems.
(BMC Cancer, 2008-11-25)
BACKGROUND: Stage at diagnosis plays a significant role in colorectal cancer (CRC) survival. Understanding which factors contribute to a more advanced stage at diagnosis is vital to improving overall survival. Comorbidity, ...