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Construct and differential item functioning in the assessment of prescription opioid use disorders among American adolescents. 

Wu, Li-Tzy; Ringwalt, Christopher L; Yang, Chongming; Reeve, Bryce B; Pan, Jeng-Jong; Blazer, Dan G (Journal of the American Academy of Child and Adolescent Psychiatry, 2009-05)
OBJECTIVE:To examine the psychometric properties of diagnostic criteria for prescription analgesic opioid use disorders (OUDs) and to identify background predictors of a latent continuum for OUD liability. METHOD:Data were ...
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Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. 

Levesque, Marc C; Moody, M Anthony; Hwang, Kwan-Ki; Marshall, Dawn J; Whitesides, John F; Amos, Joshua D; Gurley, Thaddeus C; ... (25 authors) (PLoS Med, 2009-07-07)
BACKGROUND: The antibody response to HIV-1 does not appear in the plasma until approximately 2-5 weeks after transmission, and neutralizing antibodies to autologous HIV-1 generally do not become detectable until 12 weeks ...
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The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer. 

Guan, Xiaoxiang; Zhao, Hui; Niu, Jiangong; Tang, Dongfeng; Ajani, Jaffer A; Wei, Qingyi (BMC gastroenterology, 2009-10-16)
Both TGF-beta1 and VEGF play a critic role in the multiple-step process of tumorgenesis of gastric cancer. Single nucleotide polymorphisms (SNPs) of the TGFB1 and VEGF genes have been associated with risk and progression ...
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Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study. 

Reardon, DA; Desjardins, A; Vredenburgh, JJ; Gururangan, S; Sampson, JH; Sathornsumetee, S; McLendon, RE; ... (13 authors) (Br J Cancer, 2009-12-15)
BACKGROUND: We evaluated bevacizumab with metronomic etoposide among recurrent malignant glioma patients in a phase 2, open-label trial. METHODS: A total of 59 patients, including 27 with glioblastoma (GBM) and 32 with grade ...
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Common genetic variation and the control of HIV-1 in humans. 

Fellay, Jacques; Ge, Dongliang; Shianna, Kevin V; Colombo, Sara; Ledergerber, Bruno; Cirulli, Elizabeth T; Urban, Thomas J; ... (38 authors) (PLoS Genet, 2009-12)
To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants ...
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Resolving response, decision, and strategic control: evidence for a functional topography in dorsomedial prefrontal cortex. 

Venkatraman, Vinod; Rosati, Alexandra G; Taren, Adrienne A; Huettel, Scott A (J Neurosci, 2009-10-21)
The dorsomedial prefrontal cortex (DMPFC) plays a central role in aspects of cognitive control and decision making. Here, we provide evidence for an anterior-to-posterior topography within the DMPFC using tasks that evoke ...
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Dominance, politics, and physiology: voters' testosterone changes on the night of the 2008 United States presidential election. 

Stanton, Steven J; Beehner, Jacinta C; Saini, Ekjyot K; Kuhn, Cynthia M; Labar, Kevin S (PLoS One, 2009-10-21)
BACKGROUND: Political elections are dominance competitions. When men win a dominance competition, their testosterone levels rise or remain stable to resist a circadian decline; and when they lose, their testosterone levels ...
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Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis. 

Shah, Svati H; Freedman, Neil J; Zhang, Lisheng; Crosslin, David R; Stone, David H; Haynes, Carol; Johnson, Jessica; ... (22 authors) (PLoS Genet, 2009-01)
Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, ...

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AuthorHaynes, Barton F (2)Ajani, Jaffer A (1)Allgood, Sallie (1)Amos, Joshua D (1)Antonarakis, Stylianos E (1)Beckmann, Jacques S (1)Beehner, Jacinta C (1)Bigner, DD (1)Blazer, Dan G (1)Carrington, Mary (1)... View MoreDate Issued
2009 (8)
TypeJournal article (8)Subject
Female (8)
Humans (8)
Male (8)Adult (5)Middle Aged (4)Alleles (3)Genotype (3)Adolescent (2)Aged (2)Genetic Predisposition to Disease (2)... View MoreAffiliation of Duke Author(s)
Basic Science Departments (8)
Duke (8)School of Medicine (8)Clinical Science Departments (7)Institutes and Centers (7)Duke Cancer Institute (6)Medicine (6)Institutes and Provost's Academic Units (5)University Institutes and Centers (5)Duke Institute for Brain Sciences (4)... View More
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