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Trade-offs between cancer and other diseases: do they exist and influence longevity? 

Akushevich, Igor; Akushevich, L; Arbeev, Konstantin; Arbeeva, L; Culminskaya, IV; Kulminski, Alexander; Ukraintseva, Svetlana; ... (8 authors) (Rejuvenation Res, 2010-08)
Relationships between aging, disease risks, and longevity are not yet well understood. For example, joint increases in cancer risk and total survival observed in many human populations and some experimental aging studies ...
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Medical cost trajectories and onsets of cancer and noncancer diseases in US elderly population. 

Akushevich, Igor; Kravchenko, Julia; Akushevich, Lucy; Ukraintseva, Svetlana; Arbeev, Konstantin; Yashin, Anatoliy I (Comput Math Methods Med, 2011)
Time trajectories of medical costs-associated with onset of twelve aging-related cancer and chronic noncancer diseases were analyzed using the National Long-Term Care Survey data linked to Medicare Service Use files. A special ...
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Age trajectories of physiological indices in relation to healthy life course. 

Arbeev, Konstantin G; Ukraintseva, Svetlana V; Akushevich, Igor; Kulminski, Alexander M; Arbeeva, Liubov S; Akushevich, Lucy; Culminskaya, Irina V; ... (8 authors) (Mech Ageing Dev, 2011-03)
We analysed relationship between the risk of onset of "unhealthy life" (defined as the onset of cancer, cardiovascular diseases, or diabetes) and longitudinal changes in body mass index, diastolic blood pressure, hematocrit, ...
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Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data. 

Arbeev, Konstantin G; Ukraintseva, Svetlana V; Arbeeva, Liubov S; Akushevich, Igor; Kulminski, Alexander M; Yashin, Anatoliy I (Biogerontology, 2011-04)
Small sample size of genetic data is often a limiting factor for desirable accuracy of estimated genetic effects on age-specific risks and survival. Longitudinal non-genetic data containing information on survival or disease ...
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Morbidity risks among older adults with pre-existing age-related diseases. 

Akushevich, Igor; Kravchenko, Julia; Ukraintseva, Svetlana; Arbeev, Konstantin; Kulminski, Alexander; Yashin, Anatoliy I (Exp Gerontol, 2013-12)
Multi-morbidity is common among older adults; however, for many aging-related diseases there is no information for U.S. elderly population on how earlier-manifested disease affects the risk of another disease manifested ...
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Variability in the treatment of elderly patients with stage IIIA (N2) non-small-cell lung cancer. 

Berry, Mark F; Worni, Mathias; Pietrobon, Ricardo; D'Amico, Thomas A; Akushevich, Igor (J Thorac Oncol, 2013-06)
INTRODUCTION: : We evaluated treatment patterns of elderly patients with stage IIIA (N2) non-small-cell lung cancer (NSCLC). METHODS: : The use of surgery, chemotherapy, and radiation for patients with stage IIIA (T1-T3N2M0) ...
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Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis. 

Akushevich, Igor; Kravchenko, Julia; Ukraintseva, Svetlana; Arbeev, Konstantin; Yashin, Anatoly I (Age Ageing, 2013-07)
OBJECTIVES: time trends of age-adjusted incidence rates of 19 ageing-related diseases were evaluated for 1992-2005 period with the National Long Term Care Survey and the Surveillance, Epidemiology and End RESULTS Registry ...
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Exploring the association between melanoma and glioma risks. 

Scarbrough, Peter M; Akushevich, Igor; Wrensch, Margaret; Il'yasova, Dora (Ann Epidemiol, 2014-06)
PURPOSE: Gliomas are one of the most fatal malignancies, with largely unknown etiology. This study examines a possible connection between glioma and melanoma, which might provide insight into gliomas' etiology. METHODS: ...
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Benefit of adjuvant chemotherapy after resection of stage II (T1-2N1M0) non-small cell lung cancer in elderly patients. 

Berry, Mark F; Coleman, Brooke K; Curtis, Lesley H; Worni, Mathias; D'Amico, Thomas A; Akushevich, Igor (Ann Surg Oncol, 2015-02)
BACKGROUND: We evaluated the use and efficacy of adjuvant chemotherapy after resection of T1-2N1M0 non-small cell lung cancer (NSCLC) in elderly patients. METHODS: Factors associated with the use of adjuvant chemotherapy ...
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How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity. 

Yashin, Anatoliy I; Arbeev, Konstantin G; Arbeeva, Liubov S; Wu, Deqing; Akushevich, Igor; Kovtun, Mikhail; Yashkin, Arseniy; ... (12 authors) (Biogerontology, 2016-02)
Increasing proportions of elderly individuals in developed countries combined with substantial increases in related medical expenditures make the improvement of the health of the elderly a high priority today. If the process ...
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Akushevich, Igor (19)
Kravchenko, Julia (7)Yashin, Anatoliy I (7)Arbeev, Konstantin (6)Arbeev, Konstantin G (5)Ukraintseva, Svetlana (5)Ukraintseva, Svetlana V (5)Worni, Mathias (5)Pietrobon, Ricardo (4)Akushevich, Lucy (3)... View MoreDate Issued2012 (4)2013 (4)2010 (3)2011 (3)2014 (3)2015 (1)2016 (1)2017 (1)TypeJournal article (20)SubjectFemale (20)Humans (20)
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