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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.

Bloomfield, Gerald; Carter, EJ; Hogan, JW; Keter, A; Kimaiyo, S; Sang, E; Velazquez, Eric J (PLoS One, 2011)

BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related cardiovascular risk research is largely derived ...

Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.

Akwanalo, CO; Bloomfield, Gerald; Chen, P-S; Emonyi, W; Heckbert, SR; Inui, TS; Kimaiyo, S; ... (16 authors) (PLoS One, 2017)

BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular disease burden. The clinical profile and outcomes of AF patients with valvular heart diseases in sub-Saharan Africa (SSA) have not ...

Simplified Predictive Instrument to Rule Out Acute Coronary Syndromes in a High-Risk Population.

Fanaroff, Alexander C; Schulteis, Ryan D; Pieper, Karen S; Rao, Sunil V; Newby, L Kristin (J Am Heart Assoc, 2015-12-14)

BACKGROUND: It is unclear whether diagnostic protocols based on cardiac markers to identify low-risk chest pain patients suitable for early release from the emergency department can be applied to patients older than 65 years ...

Ventricular conduction and long-term heart failure outcomes and mortality in African Americans: insights from the Jackson Heart Study.

Mentz, Robert J; Greiner, Melissa A; DeVore, Adam D; Dunlay, Shannon M; Choudhary, Gaurav; Ahmad, Tariq; Khazanie, Prateeti; ... (14 authors) (Circ Heart Fail, 2015-03)

BACKGROUND: QRS prolongation is associated with adverse outcomes in mostly white populations, but its clinical significance is not well established for other groups. We investigated the association between QRS duration and ...

Catheter Ablation of Atrial Fibrillation in U.S. Community Practice--Results From Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).

Holmqvist, Fredrik; Simon, DaJuanicia; Steinberg, Benjamin A; Hong, Seok Jae; Kowey, Peter R; Reiffel, James A; Naccarelli, Gerald V; ... (12 authors) (J Am Heart Assoc, 2015-05-21)

BACKGROUND: The characteristics of patients undergoing atrial fibrillation (AF) ablation and subsequent outcomes in community practice are not well described. METHODS AND RESULTS: Using the Outcomes Registry for Better Informed ...

Torsemide versus furosemide in heart failure patients: insights from Duke University Hospital.

Mentz, Robert J; Buggey, Jonathan; Fiuzat, Mona; Ersbøll, Mads K; Schulte, Phillip J; DeVore, Adam D; Eisenstein, Eric L; ... (10 authors) (J Cardiovasc Pharmacol, 2015-05)

Furosemide has historically been the primary loop diuretic in heart failure patients despite data suggesting potential advantages with torsemide. We used the Duke Echocardiography Lab Database to investigate patients admitted ...

Relief and Recurrence of Congestion During and After Hospitalization for Acute Heart Failure: Insights From Diuretic Optimization Strategy Evaluation in Acute Decompensated Heart Failure (DOSE-AHF) and Cardiorenal Rescue Study in Acute Decompensated Heart Failure (CARESS-HF).

Lala, Anuradha; McNulty, Steven E; Mentz, Robert J; Dunlay, Shannon M; Vader, Justin M; AbouEzzeddine, Omar F; DeVore, Adam D; ... (15 authors) (Circ Heart Fail, 2015-07)

BACKGROUND: Congestion is the most frequent cause for hospitalization in acute decompensated heart failure. Although decongestion is a major goal of acute therapy, it is unclear how the clinical components of congestion ...

Cognitive Function: Is There More to Anticoagulation in Atrial Fibrillation Than Stroke?

Cao, Lin; Pokorney, Sean D; Hayden, Kathleen; Welsh-Bohmer, Kathleen; Newby, L Kristin (J Am Heart Assoc, 2015-08-03)

Impact of fibrinogen levels on angiographic progression and 12-year survival in the armed forces regression study.

Devendra, Ganesh P; Hart, Stephen A; Whitney, Edwin J; Krasuski, Richard A (Angiology, 2010-05)

We assessed the role of fibrinogen levels on angiographic progression and long-term survival among 111 patients with coronary disease enrolled in the Armed Forces Regression Study (AFREGS). Baseline fibrinogen levels and ...

Impact of increases in high-density lipoprotein cholesterol on cardiovascular outcomes during the armed forces regression study.

Devendra, Ganesh P; Whitney, Edwin J; Krasuski, Richard A (J Cardiovasc Pharmacol Ther, 2010-12)

INTRODUCTION: high-density lipoprotein (HDL) cholesterol is a well-established inverse risk factor for cardiovascular disease. The extent to which cardiovascular risk can be modified through changes in HDL, however, is less ...