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Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations.
(Hepatology (Baltimore, Md.), 2014-02)
Drug-induced liver injury (DILI) is considered to be a diagnosis of exclusion. Liver
biopsy may contribute to diagnostic accuracy, but the histological features of DILI
and their relationship to biochemical parameters and ...
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
(Crit Care Med, 1993-01)
OBJECTIVES: To determine whether a continuous i.v. infusion of cimetidine, a histamine-2
(H2) receptor antagonist, is needed to prevent upper gastrointestinal (GI) hemorrhage
when compared with placebo and if that usage ...
Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...
Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations.
(Scientific reports, 2015-01)
Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway
may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1
and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...
Preoperative predictors of extended hospital length of stay following total knee arthroplasty.
(J Arthroplasty, 2015-03)
The purpose of this study was to identify the preoperative predictors of hospital
length of stay after primary total knee arthroplasty in a patient population reflecting
current trends toward shorter hospitalization and ...
Patient expectation is the most important predictor of discharge destination after primary total joint arthroplasty.
(J Arthroplasty, 2015-04)
The purpose of this study was to identify preoperative predictors of discharge destination
after total joint arthroplasty. A retrospective study of three hundred and seventy-two
consecutive patients who underwent primary ...
Renal systems biology of patients with systemic inflammatory response syndrome.
(Kidney Int, 2015-10)
A systems biology approach was used to comprehensively examine the impact of renal
disease and hemodialysis (HD) on patient response during critical illness. To achieve
this, we examined the metabolome, proteome, ...
Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.
(Clin Infect Dis, 2015-11-01)
BACKGROUND: Lyme disease is diagnosed by 2-tiered serologic testing in patients with
a compatible clinical illness, but the significance of positive test results in low-prevalence
regions has not been investigated. METHODS: ...
A randomized Phase 2 trial of telavancin versus standard therapy in patients with uncomplicated Staphylococcus aureus bacteremia: the ASSURE study.
(BMC Infect Dis, 2014-05-23)
BACKGROUND: Staphylococcus aureus bacteremia is a common infection associated with
significant morbidity and mortality. Telavancin is a bactericidal lipoglycopeptide
active against Gram-positive pathogens, including ...