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Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.
(Clin Infect Dis, 2015-11-01)
BACKGROUND: Lyme disease is diagnosed by 2-tiered serologic testing in patients with
a compatible clinical illness, but the significance of positive test results in low-prevalence
regions has not been investigated. METHODS: ...
Adult age differences in functional connectivity during executive control.
(Neuroimage, 2010-08-15)
Task switching requires executive control processes that undergo age-related decline.
Previous neuroimaging studies have identified age-related differences in brain activation
associated with global switching effects (dual-task ...
Geographic differences in the prevalence of hypertension in Uganda: Results of a national epidemiological study.
(PloS one, 2018-01)
BACKGROUND:Hypertension accounts for more than 212 million global disability-adjusted
life-years, and more than 15 million in sub-Saharan Africa. Identifying factors underlying
the escalating burden of hypertension in sub-Saharan ...
Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection.
(Clin Infect Dis, 2010-09-15)
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of
complicated skin and skin-structure infection (cSSSI). Increasing antimicrobial resistance
in cSSSI has led to a need for new safe and effective ...
Comorbid substance use disorders with other Axis I and II mental disorders among treatment-seeking Asian Americans, Native Hawaiians/Pacific Islanders, and mixed-race people.
(Journal of psychiatric research, 2013-12)
Little is known about behavioral healthcare needs of Asian Americans (AAs), Native
Hawaiians/Pacific Islanders (NHs/PIs), and mixed-race people (MRs)-the fastest growing
segments of the U.S. population. We examined substance ...
Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy.
(Am J Trop Med Hyg, 2015-02)
We describe the laboratory-confirmed etiologies of illness among participants in a
hospital-based febrile illness cohort study in northern Tanzania who retrospectively
met Integrated Management of Adolescent and Adult Illness ...
Substance use and mental diagnoses among adults with and without type 2 diabetes: Results from electronic health records data.
(Drug and alcohol dependence, 2015-11)
BACKGROUND:Comorbid diabetes and substance use diagnoses (SUD) represent a hazardous
combination, both in terms of healthcare cost and morbidity. To date, there is limited
information about the association of SUD and related ...
Host gene expression classifiers diagnose acute respiratory illness etiology.
(Sci Transl Med, 2016-01-20)
Acute respiratory infections caused by bacterial or viral pathogens are among the
most common reasons for seeking medical care. Despite improvements in pathogen-based
diagnostics, most patients receive inappropriate antibiotics. ...
Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania.
(Am J Trop Med Hyg, 2012-01)
Consecutive febrile admissions were enrolled at two hospitals in Moshi, Tanzania.
Confirmed acute Chikungunya virus (CHIKV), Dengue virus (DENV), and flavivirus infection
were defined as a positive polymerase chain reaction ...