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Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.

Allgood, S; Amos, JD; Cohen, MS; Eron, JJ; Goepfert, Paul A; Gurley, TC; Haynes, Barton Ford; ... (25 authors) (PLoS Med, 2009-07-07)

BACKGROUND: The antibody response to HIV-1 does not appear in the plasma until approximately 2-5 weeks after transmission, and neutralizing antibodies to autologous HIV-1 generally do not become detectable until 12 weeks ...

Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.

Fleming, MF; Davis, J; Passik, SD (Pain Med, 2008-11)

BACKGROUND: The aim of this report is to determine the frequency of aberrant drug behaviors and their relationship to substance abuse disorders in a large primary sample of patients receiving opioids for chronic pain. METHODS: ...

The design of an observational study of hypertension management, adherence and pressure control in Blood Pressure Success Zone Program participants.

BPSZ-BLISS Study Steering Committee; Califf, Robert M; Caro, JJ; Daley, WL; Flack, J; Ishak, KJ; Khan, ZM; ... (13 authors) (Int J Clin Pract, 2008-09)

AIMS: The Blood Pressure Success Zone (BPSZ) Program, a nationwide initiative, provides education in addition to a complimentary trial of one of three antihypertensive medications. The BPSZ Longitudinal Observational Study ...

Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance.

Becher, H; Chierakul, W; Day, NP; Fowler, Vance Garrison Jr; Hongsuwan, M; Limmathurotsakul, D; Mahavanakul, W; ... (16 authors) (PLoS One, 2009)

BACKGROUND: Most information on invasive Staphylococcus aureus infections comes from temperate countries. There are considerable knowledge gaps in epidemiology, treatment, drug resistance and outcome of invasive S. aureus ...

Substance abuse, treatment needs and access among female sex workers and non-sex workers in Pretoria, South Africa.

Wechsberg, WM; Wu, L-T; Zule, WA; Parry, CD; Browne, FA; Luseno, WK; Kline, T; ... (8 authors) (Subst Abuse Treat Prev Policy, 2009-05-27)

BACKGROUND: This study examined cross-sectional data collected from substance-using female sex workers (FSW) and non-sex workers (non-SW) in Pretoria, South Africa, who entered a randomized controlled trial. METHODS: Women ...

Plasma antibodies against heat shock protein 70 correlate with the incidence and severity of asthma in a Chinese population.

Wei, Qingyi; Yang, Miao; Wu, Tangchun; Cheng, Longxian; Wang, Feng; Tanguay, Robert M (Respiratory research, 2005-01)

BACKGROUND: The heat shock proteins (Hsps) are induced by stresses such as allergic factors and inflammatory responses in bronchi epithelial cells and therefore may be detectable in patients with asthma. However, the etiologic ...