Skip to main content
Duke University Libraries
DukeSpace Scholarship by Duke Authors
  • Login
  • Ask
  • Menu
  • Login
  • Ask a Librarian
  • Search & Find
  • Using the Library
  • Research Support
  • Course Support
  • Libraries
  • About
Search 
  •   DukeSpace
  • Duke Scholarly Works
  • Search
  •   DukeSpace
  • Duke Scholarly Works
  • Search
JavaScript is disabled for your browser. Some features of this site may not work without it.

Search

Show Advanced FiltersHide Advanced Filters

Filters

Use filters to refine the search results.

Now showing items 1-10 of 11

  • Sort Options:
  • Relevance
  • Title Asc
  • Title Desc
  • Issue Date Asc
  • Issue Date Desc
  • Results Per Page:
  • 5
  • 10
  • 20
  • 40
  • 60
  • 80
  • 100
Thumbnail

The liver kinase B1 is a central regulator of T cell development, activation, and metabolism. 

MacIver, Nancie J; Blagih, Julianna; Saucillo, Donte C; Tonelli, Luciana; Griss, Takla; Rathmell, Jeffrey C; Jones, Russell G (J Immunol, 2011-10-15)
T cell activation leads to engagement of cellular metabolic pathways necessary to support cell proliferation and function. However, our understanding of the signal transduction pathways that regulate metabolism and their ...
Thumbnail

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. 

Michalek, Ryan D; Gerriets, Valerie A; Jacobs, Sarah R; Macintyre, Andrew N; MacIver, Nancie J; Mason, Emily F; Sullivan, Sarah A; ... (9 authors) (J Immunol, 2011-03-15)
Stimulated CD4(+) T lymphocytes can differentiate into effector T cell (Teff) or inducible regulatory T cell (Treg) subsets with specific immunological roles. We show that Teff and Treg require distinct metabolic programs ...
Thumbnail

Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism. 

Cain, Derek W; Snowden, Pilar B; Sempowski, Gregory D; Kelsoe, Garnett (PLoS One, 2011)
Normally, neutrophil pools are maintained by homeostatic mechanisms that require the transcription factor C/EBPα. Inflammation, however, induces neutrophilia through a distinct pathway of "emergency" granulopoiesis that ...
Thumbnail

Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections. 

Ingram, Jennifer T; Yi, John S; Zajac, Allan J (PLoS Pathog, 2011-09)
During many chronic infections virus-specific CD8 T cells succumb to exhaustion as they lose their ability to respond to antigenic activation. Combinations of IL-12, IL-18, and IL-21 have been shown to induce the ...
Thumbnail

Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation. 

Kwun, Jean; Malarkannan, Subramaniam; Burlingham, William J; Knechtle, Stuart J (J Immunol, 2011-10-15)
Grafts can be rejected even when matched for MHC because of differences in the minor histocompatibility Ags (mH-Ags). H4- and H60-derived epitopes are known as immunodominant mH-Ags in H2(b)-compatible BALB.B to C57BL/6 ...
Thumbnail

Mitochondrial fusion is regulated by Reaper to modulate Drosophila programmed cell death. 

Thomenius, M; Freel, CD; Horn, S; Krieser, R; Abdelwahid, E; Cannon, R; Balasundaram, S; ... (9 authors) (Cell Death Differ, 2011-10)
In most multicellular organisms, the decision to undergo programmed cell death in response to cellular damage or developmental cues is typically transmitted through mitochondria. It has been suggested that an exception is ...
Thumbnail

Transmission of MRSA between companion animals and infected human patients presenting to outpatient medical care facilities. 

Ferreira, Jorge Pinto; Anderson, Kevin L; Correa, Maria T; Lyman, Roberta; Ruffin, Felicia; Reller, L Barth; Fowler, Vance G (PLoS One, 2011)
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant pathogen in both human and veterinary medicine. The importance of companion animals as reservoirs of human infections is currently unknown. The companion ...
Thumbnail

Extended-release ranolazine: critical evaluation of its use in stable angina. 

Truffa, Adriano Am; Newby, L Kristin; Melloni, Chiara (Vasc Health Risk Manag, 2011)
Coronary heart disease is the major cause of morbidity and mortality throughout the world, and is responsible for approximately one of every six deaths in the US. Angina pectoris is a clinical syndrome characterized ...
Thumbnail

Characterization of basal pseudopod-like processes in ileal and colonic PYY cells. 

Bohórquez, Diego V; Chandra, Rashmi; Samsa, Leigh Ann; Vigna, Steven R; Liddle, Rodger A (J Mol Histol, 2011-02)
The peptide tyrosine tyrosine (PYY) is produced and secreted from L cells of the gastrointestinal mucosa. To study the anatomy and function of PYY-secreting L cells, we developed a transgenic PYY-green fluorescent protein ...
Thumbnail

Membrane binding of plasmid DNA and endocytic pathways are involved in electrotransfection of mammalian cells. 

Wu, Mina; Yuan, Fan (PLoS One, 2011)
Electric field mediated gene delivery or electrotransfection is a widely used method in various studies ranging from basic cell biology research to clinical gene therapy. Yet, mechanisms of electrotransfection are still ...
  • 1
  • 2

Make Your Work Available Here

How to Deposit

Browse

All of DukeSpaceCommunities & CollectionsAuthorsTitlesTypesBy Issue DateDepartmentsAffiliations of Duke Author(s)SubjectsBy Submit DateThis CommunityAuthorsTitlesTypesBy Issue DateDepartmentsAffiliations of Duke Author(s)SubjectsBy Submit Date

My Account

LoginRegister

Discover

AuthorMacIver, Nancie J (2)Rathmell, Jeffrey C (2)Abdelwahid, E (1)Anderson, Kevin L (1)Balasundaram, S (1)Blagih, Julianna (1)Bohórquez, Diego V (1)Burlingham, William J (1)Cain, Derek W (1)Cannon, R (1)... View MoreDate Issued
2011 (11)
Type
Journal article (11)
Subject
Animals (11)
Mice (8)Humans (3)Mice, Inbred C57BL (3)CD8-Positive T-Lymphocytes (2)Cell Survival (2)Disease Models, Animal (2)Flow Cytometry (2)Lymphocyte Activation (2)Mice, Knockout (2)... View MoreAffiliation of Duke Author(s)
Clinical Science Departments (11)
Duke (11)
Institutes and Centers (11)
School of Medicine (11)Basic Science Departments (7)Duke Cancer Institute (6)Medicine (5)Pathology (4)Duke Clinical Research Institute (3)Immunology (3)... View More
Duke University Libraries

Contact Us

411 Chapel Drive
Durham, NC 27708
(919) 660-5870
Perkins Library Service Desk

Digital Repositories at Duke

  • Report a problem with the repositories
  • About digital repositories at Duke
  • Accessibility Policy
  • Deaccession and DMCA Takedown Policy

TwitterFacebookYouTubeFlickrInstagramBlogs

Sign Up for Our Newsletter
  • Re-use & Attribution / Privacy
  • Support the Libraries
Duke University