Browsing Scholarly Articles by Subject "Dactinomycin"

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Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations.

Fullwood, Melissa J; Lee, Joanne; Lin, Lifang; Li, Guoliang; Huss, Mikael; Ng, Patrick; Sung, Wing-Kin; ... (8 authors) (PLoS One, 2011)

DNA fragmentation is a well-recognized hallmark of apoptosis. However, the precise DNA sequences cleaved during apoptosis triggered by distinct mechanisms remain unclear. We used next-generation sequencing of DNA fragments ...