Browsing Scholarly Articles by Subject "X-Box Binding Protein 1"

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Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency.

Homa, Nicholas J; Salinas, Raul; Forte, Eleonora; Robinson, Timothy J; Garcia-Blanco, Mariano A; Luftig, Micah A (Journal of virology, 2013-11)

Oncogenic viruses promote cell proliferation through the dramatic reorganization of host transcriptomes. In addition to regulating mRNA abundance, changes in mRNA isoform usage can have a profound impact on the protein output ...
XBP1 (X-Box-Binding Protein-1)-Dependent O-GlcNAcylation Is Neuroprotective in Ischemic Stroke in Young Mice and Its Impairment in Aged Mice Is Rescued by Thiamet-G.

Jiang, Meng; Yu, Shu; Yu, Zhui; Sheng, Huaxin; Li, Ying; Liu, Shuai; Warner, David S; ... (9 authors) (Stroke, 2017-06)

<h4>Background and purpose</h4>Impaired protein homeostasis induced by endoplasmic reticulum dysfunction is a key feature of a variety of age-related brain diseases including stroke. To restore endoplasmic reticulum function ...