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Now showing items 1-10 of 11
Recovery and survival from aging-associated diseases.
(Exp Gerontol, 2013-08)
OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan
of the US elderly population may lead to erroneous conclusions when recovery/long-term
remission factors are underestimated. Using two ...
Leukocyte telomere length, breast cancer risk in the offspring: the relations with father's age at birth.
(Mech Ageing Dev, 2011-04)
Recent studies have reported that leukocyte telomere length (LTL) is longer in offspring
of older fathers. Longer telomeres might increase cancer risk. We examined the relation
of father's age at the birth of the offspring ...
Trade-offs in the effects of the apolipoprotein E polymorphism on risks of diseases of the heart, cancer, and neurodegenerative disorders: insights on mechanisms from the Long Life Family Study.
(Rejuvenation Res, 2015-04)
The lack of evolutionary established mechanisms linking genes to age-related traits
makes the problem of genetic susceptibility to health span inherently complex. One
complicating factor is genetic trade-off. Here we focused ...
Medical cost trajectories and onsets of cancer and noncancer diseases in US elderly population.
(Comput Math Methods Med, 2011)
Time trajectories of medical costs-associated with onset of twelve aging-related cancer
and chronic noncancer diseases were analyzed using the National Long-Term Care Survey
data linked to Medicare Service Use files. A special ...
Cardiovascular comorbidities and survival of lung cancer patients: Medicare data based analysis.
(Lung Cancer, 2017-06-05)
OBJECTIVES: To evaluate the role of cardiovascular disease (CVD) comorbidity in survival
of patients with non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: The impact
of seven CVDs (at the time of NSCLC diagnosis ...
Biogenetic mechanisms predisposing to complex phenotypes in parents may function differently in their children.
(J Gerontol A Biol Sci Med Sci, 2013-07)
This study focuses on the participants of the Long Life Family Study to elucidate
whether biogenetic mechanisms underlying relationships among heritable complex phenotypes
in parents function in the same way for the same ...
Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis.
(J Am Geriatr Soc, 2012-02)
OBJECTIVES: To use the Medicare Files of Service Use (MFSU) to evaluate patterns in
the incidence of aging-related diseases in the U.S. elderly population. DESIGN: Age-specific
incidence rates of 19 aging-related diseases ...
Leukocyte telomere length is associated with disability in older u.s. Population.
(J Am Geriatr Soc, 2010-07)
OBJECTIVES: To determine whether mean leukocyte telomere length (LTL) serves as a
biomarker of disability assessed according to activities of daily living (ADLs) and
what factors may modify this relationship. DESIGN: ...
Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits.
(Mech Ageing Dev, 2011-04)
We used an approach of cumulative deficits to evaluate the rate of aging in 4954 participants
of the Long-Life Family Study (LLFS) recruited in the U.S. (Boston, New York, and
Pittsburgh) and Denmark. We used an array of ...
Morbidity risks among older adults with pre-existing age-related diseases.
(Exp Gerontol, 2013-12)
Multi-morbidity is common among older adults; however, for many aging-related diseases
there is no information for U.S. elderly population on how earlier-manifested disease
affects the risk of another disease manifested ...