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Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 

Ma, Hongxia; Wang, Li-E; Liu, Zhensheng; Sturgis, Erich M; Wei, Qingyi (BMC cancer, 2011-06-20)
Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase family plays crucial roles in carcinogenesis and progression of several cancers, including squamous cell carcinoma of the head and neck ...
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A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population. 

Zhou, Keke; Hu, Dezhi; Lu, Juan; Fan, Weiwei; Liu, Hongliang; Chen, Hongyan; Chen, Gong; ... (12 authors) (BMC cancer, 2011-01)
BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1 (APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1 promoter -141T/G variant (rs1760944) has been reported ...
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Genome-wide association study identifies three new melanoma susceptibility loci. 

Barrett, Jennifer H; Iles, Mark M; Harland, Mark; Taylor, John C; Aitken, Joanne F; Andresen, Per Arne; Akslen, Lars A; ... (76 authors) (Nature genetics, 2011-10-09)
We report a genome-wide association study for melanoma that was conducted by the GenoMEL Consortium. Our discovery phase included 2,981 individuals with melanoma and 1,982 study-specific control individuals of European ancestry, ...

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Author
Wei, Qingyi (3)
Aitken, Joanne F (1)Akslen, Lars A (1)Amos, Christopher I (1)Andresen, Per Arne (1)Armstrong, Bruce K (1)Avril, Marie-Francoise (1)Azizi, Esther (1)Bakker, Bert (1)Barrett, Jennifer H (1)... View MoreDate Issued
2011 (3)
TypeJournal article (3)SubjectCase-Control Studies (3)
Genetic Predisposition to Disease (3)
Humans (3)
Polymorphism, Single Nucleotide (3)
Female (2)Genome-Wide Association Study (2)Genotype (2)Male (2)Middle Aged (2)Risk Factors (2)... View MoreAffiliation of Duke Author(s)Basic Science Departments (3)Clinical Science Departments (3)Duke (3)Duke Cancer Institute (3)Institutes and Centers (3)
Medicine (3)
Medicine, Medical Oncology (3)Population Health Sciences (3)School of Medicine (3)Staff (1)
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