Now showing items 301-310 of 326
WARREN'S "WORST" BOOK
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor.
(Proc Natl Acad Sci U S A, 1999-10-26)
Several G-protein coupled receptors, such as the beta1-adrenergic receptor (beta1-AR), contain polyproline motifs within their intracellular domains. Such motifs in other proteins are known to mediate protein-protein interactions ...
Cost of innovation in the pharmaceutical industry.
(J Health Econ, 1991-07)
The research and development costs of 93 randomly selected new chemical entities (NCEs) were obtained from a survey of 12 U.S.-owned pharmaceutical firms. These data were used to estimate the pre-tax average cost of new ...
Health Reform and Pharmaceutical Innovation
(Seton Hall Law Review, 1994)
Diseased G protein-coupled receptors.
(J Clin Invest, 1993-11)
On Responsibility and Punishment
The litany of social dysfunction is now familiar. The rates of violent crime are higher than they have ever been: Americans kill and maim one another at per-capita rates an order of magnitude higher than other industrialized ...
Mid-Cretaceous strontium-isotope stratigraphy of deep-sea sections
(GEOLOGICAL SOCIETY OF AMERICA BULLETIN, 1997-11)
Holiness of Heart and Life: Lessons from North American Methodism
(Asbury Theological Journal, 1995-09-01)
beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.
(Proc Natl Acad Sci U S A, 1998-11-24)
G protein-coupled receptor activation leads to the membrane recruitment and activation of G protein-coupled receptor kinases, which phosphorylate receptors and lead to their inactivation. We have identified a novel ...