Now showing items 31-40 of 394
TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour.
(Nat Commun, 2014-09-02)
Animals need to sense and react to potentially dangerous environments. TRP ion channels participate in nociception, presumably via Ca(2+) influx, in most animal species. However, the relationship between ion permeation and ...
Component neural systems for the creation of emotional memories during free viewing of a complex, real-world event.
(Frontiers in Human Neuroscience, 2010)
Improved Visual Cognition through Stroboscopic Training.
(Front Psychol, 2011)
Humans have a remarkable capacity to learn and adapt, but surprisingly little research has demonstrated generalized learning in which new skills and strategies can be used flexibly across a range of tasks and contexts. In ...
A whole-cell and single-channel study of the voltage-dependent outward potassium current in avian hepatocytes.
(J Gen Physiol, 1988-02)
Voltage-dependent membrane currents were studied in dissociated hepatocytes from chick, using the patch-clamp technique. All cells had voltage-dependent outward K+ currents; in 10% of the cells, a fast, transient, ...
Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia.
(PLoS One, 2014)
Female sex is associated with improved outcome in experimental brain injury models, such as traumatic brain injury, ischemic stroke, and intracerebral hemorrhage. This implies female gonadal steroids may be neuroprotective. ...
Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.
(Sci Rep, 2016-06-01)
TRPV4 ion channels represent osmo-mechano-TRP channels with pleiotropic function and wide-spread expression. One of the critical functions of TRPV4 in this spectrum is its involvement in pain and inflammation. However, few ...
Modeling an Excitable Biosynthetic Tissue with Inherent Variability for Paired Computational-Experimental Studies.
(PLoS Comput Biol, 2017-01)
To understand how excitable tissues give rise to arrhythmias, it is crucially necessary to understand the electrical dynamics of cells in the context of their environment. Multicellular monolayer cultures have proven useful ...
Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure.
High blood pressure increases the risks of stroke, dementia, and neurocognitive dysfunction. Although aerobic exercise and dietary modifications have been shown to reduce blood pressure, no randomized trials have examined ...
Advances in neuroscience.
(Sci Adv, 2017-11)
Task difficulty modulates brain activation in the emotional oddball task.
(Brain Res, 2017-06-01)
Previous functional magnetic resonance imaging (fMRI) studies have reported that task-irrelevant, emotionally salient events can disrupt target discrimination, particularly when attentional demands are low, while others ...