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Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk.
(Proceedings of the National Academy of Sciences of the United States of America, 2013-11)
Achieving an AIDS-free generation will require elimination of postnatal transmission
of HIV-1 while maintaining the nutritional and immunologic benefits of breastfeeding
for infants in developing regions. Maternal/infant ...
HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.
(Journal of virology, 2018-04)
Induction of broadly cross-reactive antiviral humoral responses with the capacity
to target globally diverse circulating strains is a key goal for HIV-1 immunogen design.
A major gap in the field is the identification of ...
Strategic allocation of attention reduces temporally predictable stimulus conflict.
(J Cogn Neurosci, 2012-09)
Humans are able to continuously monitor environmental situations and adjust their
behavioral strategies to optimize performance. Here we investigate the behavioral
and brain adjustments that occur when conflicting stimulus ...
The dynamics of proactive and reactive cognitive control processes in the human brain.
(J Cogn Neurosci, 2014-05)
In this study, we leveraged the high temporal resolution of EEG to examine the neural
mechanisms underlying the flexible regulation of cognitive control that unfolds over
different timescales. We measured behavioral and ...
Differentiating sensitivity of post-stimulus undershoot under diffusion weighting: implication of vascular and neuronal hierarchy.
(PLoS One, 2008-08-13)
The widely used blood oxygenation level dependent (BOLD) signal during brain activation,
as measured in typical fMRI methods, is composed of several distinct phases, the last
of which, and perhaps the least understood, is ...
Steps to Health employee weight management randomized control trial: short-term follow-up results.
(J Occup Environ Med, 2015-02)
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study,
a randomized trial to evaluate the effectiveness of two employee weight management
programs offered within Duke University and the Health ...
A flexible statistical model for alignment of label-free proteomics data--incorporating ion mobility and product ion information.
(BMC Bioinformatics, 2013-12-16)
BACKGROUND: The goal of many proteomics experiments is to determine the abundance
of proteins in biological samples, and the variation thereof in various physiological
conditions. High-throughput quantitative proteomics, ...
Dopamine regulation of human speech and bird song: a critical review.
(Brain Lang, 2012-09)
To understand the neural basis of human speech control, extensive research has been
done using a variety of methodologies in a range of experimental models. Nevertheless,
several critical questions about learned vocal motor ...
The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus.
(Proc Natl Acad Sci U S A, 1999-02-16)
Estrogen (E) and progesterone (P) orchestrate many cellular responses involved in
female reproductive physiology, including reproductive behaviors. E- and P-binding
neurons important for lordosis behavior have been located ...
Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.
(J Virol, 2015-10)
UNLABELLED: Infants born to HIV-1-infected mothers in resource-limited areas where
replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout
breastfeeding. Despite this, the majority of infants ...