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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.
(PLoS One, 2017)
BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular
disease burden. The clinical profile and outcomes of AF patients with valvular heart
diseases in sub-Saharan Africa (SSA) have not ...
Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.
(PloS one, 2019-01)
BACKGROUND:The highest burden of disease from hepatitis C virus (HCV) is found in
Southeast Asia, but our understanding of the epidemiology of infection in many heavily
burdened countries is still limited. In particular, ...
Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study.
(BMC Nephrol, 2012-12-06)
BACKGROUND: Evidence is lacking to inform providers' and patients' decisions about
many common treatment strategies for patients with end stage renal disease (ESRD).
METHODS/DESIGN: The DEcIDE Patient Outcomes in ESRD Study ...
Safety and efficacy of ledipasvir-sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data.
(Hepatology, 2016-02)
UNLABELLED: Black patients chronically infected with genotype 1 hepatitis C virus
(HCV) have historically had lower rates of response to interferon-based treatment
than patients of other races. In the phase 3 ION program, ...
Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...
Psychiatric correlates of snuff and chewing tobacco use.
(PLoS One, 2014)
Compared to the association between cigarette smoking and psychiatric disorders, relatively
little is known about the relationship between smokeless tobacco use and psychiatric
disorders. To identify the psychiatric correlates ...
Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania.
(Int J Dermatol, 2015-01)
Abnormal skin findings are identified in over 90% of human immunodeficiency virus
(HIV)-infected persons globally. A prospective cohort study of HIV-infected patients
with skin complaints commencing antiretroviral therapy ...
Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations.
(Scientific reports, 2015-01)
Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway
may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1
and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...
Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial.
(Trials, 2015-04-30)
BACKGROUND: Despite the high prevalence and global impact of knee osteoarthritis (KOA),
current treatments are palliative. No disease modifying anti-osteoarthritic drug (DMOAD)
has been approved. We recently demonstrated ...