Now showing items 1-4 of 4
Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.
(J Clin Invest, 2011-03)
Allergic asthma is characterized by airway hyperresponsiveness, inflammation, and a cellular infiltrate dominated by eosinophils. Numerous epidemiological studies have related the exacerbation of allergic asthma with an ...
Epigenetic regulation of the nitrosative stress response and intracellular macrophage survival by extraintestinal pathogenic Escherichia coli.
(Mol Microbiol, 2012-03)
Extraintestinal pathogenic Escherichia coli (ExPEC) reside in the enteric tract as a commensal reservoir, but can transition to a pathogenic state by invading normally sterile niches, establishing infection and disseminating ...
Functional evolution of mammalian odorant receptors.
(PLoS Genet, 2012)
The mammalian odorant receptor (OR) repertoire is an attractive model to study evolution, because ORs have been subjected to rapid evolution between species, presumably caused by changes of the olfactory system to adapt ...
Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity.
(Dev Cell, 2008-07)
The endoplasmic reticulum stress response, also known as the unfolded protein response (UPR), has been implicated in the normal physiology of immune defense and in several disorders, including diabetes, cancer, ...