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Functional evolution of mammalian odorant receptors.
The ability to detect small volatile molecules in the environment is mediated by the large repertoire of odorant receptors (ORs) in each species. The mammalian OR repertoire is an attractive model to study evolution because ...
Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity.
The first line of defense against pathogens is the phylogenetically ancient innate immune system. This system consists of physical barriers and conserved signaling pathways are activated upon infection to produce effector ...