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The toxicology of climate change: environmental contaminants in a warming world.

dc.contributor.author Clark, BW
dc.contributor.author Erwin, KN
dc.contributor.author Levin, Edward Daniel
dc.contributor.author McElwee, MK
dc.contributor.author Miller, HD
dc.contributor.author Noyes, PD
dc.contributor.author Van Tiem, LA
dc.contributor.author Walcott, KC
dc.coverage.spatial Netherlands
dc.date.accessioned 2013-05-01T18:00:46Z
dc.date.issued 2009-08
dc.identifier https://www.ncbi.nlm.nih.gov/pubmed/19375165
dc.identifier S0160-4120(09)00054-3
dc.identifier.uri http://hdl.handle.net/10161/6983
dc.description.abstract Climate change induced by anthropogenic warming of the earth's atmosphere is a daunting problem. This review examines one of the consequences of climate change that has only recently attracted attention: namely, the effects of climate change on the environmental distribution and toxicity of chemical pollutants. A review was undertaken of the scientific literature (original research articles, reviews, government and intergovernmental reports) focusing on the interactions of toxicants with the environmental parameters, temperature, precipitation, and salinity, as altered by climate change. Three broad classes of chemical toxicants of global significance were the focus: air pollutants, persistent organic pollutants (POPs), including some organochlorine pesticides, and other classes of pesticides. Generally, increases in temperature will enhance the toxicity of contaminants and increase concentrations of tropospheric ozone regionally, but will also likely increase rates of chemical degradation. While further research is needed, climate change coupled with air pollutant exposures may have potentially serious adverse consequences for human health in urban and polluted regions. Climate change producing alterations in: food webs, lipid dynamics, ice and snow melt, and organic carbon cycling could result in increased POP levels in water, soil, and biota. There is also compelling evidence that increasing temperatures could be deleterious to pollutant-exposed wildlife. For example, elevated water temperatures may alter the biotransformation of contaminants to more bioactive metabolites and impair homeostasis. The complex interactions between climate change and pollutants may be particularly problematic for species living at the edge of their physiological tolerance range where acclimation capacity may be limited. In addition to temperature increases, regional precipitation patterns are projected to be altered with climate change. Regions subject to decreases in precipitation may experience enhanced volatilization of POPs and pesticides to the atmosphere. Reduced precipitation will also increase air pollution in urbanized regions resulting in negative health effects, which may be exacerbated by temperature increases. Regions subject to increased precipitation will have lower levels of air pollution, but will likely experience enhanced surface deposition of airborne POPs and increased run-off of pesticides. Moreover, increases in the intensity and frequency of storm events linked to climate change could lead to more severe episodes of chemical contamination of water bodies and surrounding watersheds. Changes in salinity may affect aquatic organisms as an independent stressor as well as by altering the bioavailability and in some instances increasing the toxicity of chemicals. A paramount issue will be to identify species and populations especially vulnerable to climate-pollutant interactions, in the context of the many other physical, chemical, and biological stressors that will be altered with climate change. Moreover, it will be important to predict tipping points that might trigger or accelerate synergistic interactions between climate change and contaminant exposures.
dc.language eng
dc.relation.ispartof Environ Int
dc.relation.isversionof 10.1016/j.envint.2009.02.006
dc.subject Air Pollutants
dc.subject Environmental Exposure
dc.subject Environmental Pollution
dc.subject Greenhouse Effect
dc.subject Humans
dc.subject Hypersensitivity
dc.subject Organic Chemicals
dc.subject Particulate Matter
dc.subject Pesticides
dc.subject Pulmonary Heart Disease
dc.title The toxicology of climate change: environmental contaminants in a warming world.
dc.type Journal article
pubs.author-url https://www.ncbi.nlm.nih.gov/pubmed/19375165
pubs.begin-page 971
pubs.end-page 986
pubs.issue 6
pubs.organisational-group Basic Science Departments
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Cancer Institute
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Duke Science & Society
pubs.organisational-group Environmental Sciences and Policy
pubs.organisational-group Initiatives
pubs.organisational-group Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Nicholas School of the Environment
pubs.organisational-group Pharmacology & Cancer Biology
pubs.organisational-group Psychiatry & Behavioral Sciences
pubs.organisational-group Psychiatry & Behavioral Sciences, Addictions
pubs.organisational-group Psychology and Neuroscience
pubs.organisational-group School of Medicine
pubs.organisational-group Staff
pubs.organisational-group Trinity College of Arts & Sciences
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 35
dc.identifier.eissn 1873-6750


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