Acoustic radiation force impulse imaging (ARFI) on an IVUS circular array.

dc.contributor.author

Patel, Vivek

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Dahl, Jeremy J

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Bradway, David P

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Doherty, Joshua R

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Lee, Seung Yun

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Smith, Stephen W

dc.coverage.spatial

England

dc.date.accessioned

2015-08-12T17:08:09Z

dc.date.issued

2014-04

dc.description.abstract

Our long-term goal is the detection and characterization of vulnerable plaque in the coronary arteries of the heart using intravascular ultrasound (IVUS) catheters. Vulnerable plaque, characterized by a thin fibrous cap and a soft, lipid-rich necrotic core is a precursor to heart attack and stroke. Early detection of such plaques may potentially alter the course of treatment of the patient to prevent ischemic events. We have previously described the characterization of carotid plaques using external linear arrays operating at 9 MHz. In addition, we previously modified circular array IVUS catheters by short-circuiting several neighboring elements to produce fixed beamwidths for intravascular hyperthermia applications. In this paper, we modified Volcano Visions 8.2 French, 9 MHz catheters and Volcano Platinum 3.5 French, 20 MHz catheters by short-circuiting portions of the array for acoustic radiation force impulse imaging (ARFI) applications. The catheters had an effective transmit aperture size of 2 mm and 1.5 mm, respectively. The catheters were connected to a Verasonics scanner and driven with pushing pulses of 180 V p-p to acquire ARFI data from a soft gel phantom with a Young's modulus of 2.9 kPa. The dynamic response of the tissue-mimicking material demonstrates a typical ARFI motion of 1 to 2 microns as the gel phantom displaces away and recovers back to its normal position. The hardware modifications applied to our IVUS catheters mimic potential beamforming modifications that could be implemented on IVUS scanners. Our results demonstrate that the generation of radiation force from IVUS catheters and the development of intravascular ARFI may be feasible.

dc.identifier

http://www.ncbi.nlm.nih.gov/pubmed/24554291

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36/2/98

dc.identifier.eissn

1096-0910

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https://hdl.handle.net/10161/10367

dc.language

eng

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SAGE Publications

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Ultrason Imaging

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10.1177/0161734613511595

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ARFI

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cardiac

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coronary

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intravascular

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transducer

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Catheters

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Elastic Modulus

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Elasticity Imaging Techniques

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Phantoms, Imaging

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Ultrasonography, Interventional

dc.title

Acoustic radiation force impulse imaging (ARFI) on an IVUS circular array.

dc.type

Journal article

duke.contributor.orcid

Bradway, David P|0000-0002-6613-2415

pubs.author-url

http://www.ncbi.nlm.nih.gov/pubmed/24554291

pubs.begin-page

98

pubs.end-page

111

pubs.issue

2

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Biomedical Engineering

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Clinical Science Departments

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Duke

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Pratt School of Engineering

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Radiology

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School of Medicine

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Staff

pubs.publication-status

Published

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36

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