Intraoperative renal resistive index with adjustment for aortic insufficiency for acute kidney injury prediction in cardiac surgery patients

My research interests are in the area of Cardiothoracic Anesthesiology. The main focus of my research is towards the understanding and prevention of acute kidney injury after cardiac and other major surgeries. Secondary interests include the study of analgesic strategies after cardiothoracic surgical procedures, performance of clinical trials, and perioperative transfusion and hemostasis.

My primary research areas include statistical genetics and the genetic investigation of human complex diseases and clinical outcomes. As the group leader of the Biostatistics and Clinical Outcome Group in the Department of Anesthesiology, I also have extensive experience in clinical research, applying both classical statistical modeling and modern machine learning methods to analyze clinical data. Below is a list of my research topics:"

• Statistical genetics: development statistical methods for different genetic data and phenotypic measures
• Genetics of Alzheimer's disease (AD) and age-at-onset (AAO) of AD
• Genetics of Fuchs endothelial corneal dystrophy (FECD)
• Genetic and HLA association for drug induced liver injury (DILI)
• Genetic and clinical research of postoperative outcomes, such as postoperative acute kidney injury, cognitive dysfunction, delirium, etc. 
• Biomarker research for osteoarthritis (OA) and its progression