Impact of beta-blockade premedication on image quality of ECG-gated thoracic aorta CT angiography.

dc.contributor.author

Entezari, Pegah

dc.contributor.author

Collins, Jeremy

dc.contributor.author

Chalian, Hamid

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Tore, Huseyin Gurkan

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Carr, James

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Yaghmai, Vahid

dc.date.accessioned

2019-04-02T17:58:27Z

dc.date.available

2019-04-02T17:58:27Z

dc.date.issued

2014-12

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2019-04-02T17:58:26Z

dc.description.abstract

BACKGROUND: Thoracic aortic aneurysm is one of the most common aorta pathologies worldwide, which is commonly evaluated by computed tomography angiography (CTA). One of the routine methods to improve the image quality of CTA is heart rate reduction prior to study by beta-blockade administration. PURPOSE: To assess the effect of beta-blockade on image quality of the ascending aorta in electrocardiography (ECG)-gated dual-source CTA (DSCTA) images. MATERIAL AND METHODS: In this retrospective study, ECG-gated thoracic aorta CTA images of 40 patients without beta-blocker administration were compared with ECG-gated images of 40 patients with beta-blockade. Images of the aorta were analyzed objectively and subjectively at three levels: sinus of Valsalva (sinus), sinotubular junction (STJ), and mid ascending aorta (MAA). Quantitative sharpness index (SI) and signal-to-noise ratio (SNR) were calculated and two radiologists evaluated the image quality using a 3-point scale. RESULTS: Mean heart rate in beta-blocker and non-beta-blocker groups was 61.7 beats per minute (bpm) (range, 58.1-63.9 bpm) and 72.9 bpm (range, 69.3-84.1 bpm), respectively (P < 0.05). Aorta wall SI, SNR, and subjective grading were comparable between the two groups at all three levels (P > 0.05). CONCLUSION: Beta-blocker premedication may not be necessary for imaging of ascending aorta with ECG-gated DSCTA.

dc.identifier

0284185113516950

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0284-1851

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1600-0455

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https://hdl.handle.net/10161/18298

dc.language

eng

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SAGE Publications

dc.relation.ispartof

Acta radiologica (Stockholm, Sweden : 1987)

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10.1177/0284185113516950

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Aorta, Thoracic

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Humans

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Aortic Aneurysm, Thoracic

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Adrenergic beta-Antagonists

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Radiographic Image Interpretation, Computer-Assisted

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Observer Variation

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Coronary Angiography

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Electrocardiography

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Premedication

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Retrospective Studies

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Middle Aged

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Female

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Male

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Cardiac-Gated Imaging Techniques

dc.title

Impact of beta-blockade premedication on image quality of ECG-gated thoracic aorta CT angiography.

dc.type

Journal article

duke.contributor.orcid

Chalian, Hamid|0000-0001-8357-7347

pubs.begin-page

1180

pubs.end-page

1185

pubs.issue

10

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School of Medicine

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Duke

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Radiology, Cardiothoracic Imaging

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Radiology

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Clinical Science Departments

pubs.publication-status

Published

pubs.volume

55

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