How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

dc.contributor.author

Wu, Li-Tzy

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Woody, George E

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Yang, Chongming

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Blazer, Dan G

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2020-02-03T05:44:49Z

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2020-02-03T05:44:49Z

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2011-03

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2020-02-03T05:44:49Z

dc.description.abstract

To study substance use and psychiatric disorders among prescription opioid users, heroin users, and non-opioid drug users in a national sample of adults.Analyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (N=43,093).Four groups were identified among 9140 illicit or non-prescribed drug users: heroin-other opioid users (1.0%; used heroin and other opioids), other opioid-only users (19.8%; used other opioids but never heroin), heroin-only users (0.5%; used heroin but never other opioids), and non-opioid drug users (78.7%; used drugs but never heroin or other opioids). After adjusting for variations in socioeconomic characteristics, history of substance abuse treatment, and familial substance abuse, heroin-other opioid users had greater odds of several substance use disorders (cocaine, hallucinogen, sedative, amphetamine, and tranquilizer) as compared with the other groups; heroin-only users had reduced odds of sedative and tranquilizer use disorders as compared with other opioid-only users. Non-opioid drug users had reduced odds of all substance use disorders and other mental disorders (mood, anxiety, pathological gambling, and personality) as compared with other opioid-only users. Past-year other opioid-only users also reported slightly lower scores on quality of life than past-year non-opioid drug users.All opioid use groups had higher rates of substance use disorders than non-opioid drug users, and these rates were particularly elevated among heroin-other opioid users. Findings suggest the need to distinguish between these four groups in research and treatment as they may have different natural histories and treatment needs.

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1932-0620

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1935-3227

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https://hdl.handle.net/10161/19992

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eng

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Ovid Technologies (Wolters Kluwer Health)

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Journal of addiction medicine

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10.1097/ADM.0b013e3181e0364e

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Humans

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Substance-Related Disorders

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Opioid-Related Disorders

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Heroin Dependence

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Narcotics

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Street Drugs

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Health Surveys

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Cross-Sectional Studies

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Mental Disorders

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Anxiety Disorders

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Mood Disorders

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Personality Disorders

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Psychopathology

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Interview, Psychological

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Comorbidity

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Quality of Life

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Adolescent

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Adult

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Middle Aged

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United States

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Female

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Male

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Young Adult

dc.title

How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

dc.type

Journal article

duke.contributor.orcid

Wu, Li-Tzy|0000-0002-5909-2259

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28

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35

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1

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School of Medicine

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Duke

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Center for Child and Family Policy

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Sanford School of Public Policy

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Duke Clinical Research Institute

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Institutes and Centers

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Duke Institute for Brain Sciences

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University Institutes and Centers

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Institutes and Provost's Academic Units

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Psychiatry & Behavioral Sciences, Social and Community Psychiatry

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Psychiatry & Behavioral Sciences

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Clinical Science Departments

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Medicine, General Internal Medicine

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Medicine

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Center for the Study of Aging and Human Development

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Family Medicine and Community Health

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Psychiatry & Behavioral Sciences, Geriatric Behavioral Health

pubs.publication-status

Published

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5

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