Correlation of pre-operative imaging characteristics with donor outcomes and operative difficulty in laparoscopic donor nephrectomy.
Date
2019-09-25
Journal Title
Journal ISSN
Volume Title
Repository Usage Stats
views
downloads
Citation Stats
Abstract
This study aimed to understand the relationship of pre-operative measurements and risk factors on operative time and outcomes of laparoscopic donor nephrectomy. 242 kidney donors between 2010 and 2017 were identified. Patient's demographic, anthropomorphic and operative characteristics were abstracted from the electronic medical record. Glomerular filtration rates (GFR) were documented before surgery, within 24 hours, 6, 12 and 24 months after surgery. Standard radiological measures and kidney volumes, subcutaneous and perinephric fat thicknesses were assessed by three radiologists. Data were analyzed using standard statistical measures. There was significant correlation between cranio-caudal and latero-lateral diameters (p<0.0001) and kidney volume. The left kidney was transplanted in 92.6% of cases and the larger kidney in 69.2%. Kidney choice (smaller vs larger) had no statistically significant impact on the rate of change of donor kidney function over time adjusting for age, sex and race (p=0.61). Perinephric fat thickness (+4.08 min) and surgery after 2011 were significantly correlated with operative time (p≤0.01). In conclusion, cranio-caudal diameters can be used as a surrogate measure for volume in the majority of donors. Size may not be a decisive factor for long-term donor kidney function. Perinephric fat around the donor kidney should be reported to facilitate operative planning.
Type
Department
Description
Provenance
Subjects
Citation
Permalink
Published Version (Please cite this version)
Publication Info
Schwartz, Fides R, Brian I Shaw, Reginald Lerebours, Federica Vernuccio, Francesca Rigiroli, Fernando Gonzalez, Sheng Luo, Aparna S Rege, et al. (2019). Correlation of pre-operative imaging characteristics with donor outcomes and operative difficulty in laparoscopic donor nephrectomy. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10.1111/ajt.15608 Retrieved from https://hdl.handle.net/10161/19352.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
Collections
Scholars@Duke
Brian Shaw
Reginald (Gino) Lerebours
Education: Masters Degree, Biostatistics. Harvard University. 2017
Bachelors Degree, Statistics. North Carolina State University. 2015
Overview: Gino currently collaborates with researchers, residents, and clinicians in the Departments of Surgery, Radiology and Infectious Diseases. His main research interests and experience are in statistical programming, data management, statistical modeling, statistical consulting and statistical education.
Sheng Luo
Aparna Sharad Rege
Daniele Marin
Liver Imaging
Dual Energy CT
CT Protocol Optimization
Dose Reduction Strategies for Abdominal CT Applications
Kadiyala Venkata Ravindra
Unless otherwise indicated, scholarly articles published by Duke faculty members are made available here with a CC-BY-NC (Creative Commons Attribution Non-Commercial) license, as enabled by the Duke Open Access Policy. If you wish to use the materials in ways not already permitted under CC-BY-NC, please consult the copyright owner. Other materials are made available here through the author’s grant of a non-exclusive license to make their work openly accessible.