Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care?
| dc.contributor.author | Maciejewski, Matthew L | |
| dc.contributor.author | Bosworth, Hayden B | |
| dc.contributor.author | Olsen, Maren K | |
| dc.contributor.author | Smith, Valerie A | |
| dc.contributor.author | Edelman, David | |
| dc.contributor.author | Powers, Benjamin J | |
| dc.contributor.author | Kaufman, Miriam A | |
| dc.contributor.author | Oddone, Eugene Z | |
| dc.contributor.author | Jackson, George L | |
| dc.date.accessioned | 2024-02-01T15:41:31Z | |
| dc.date.available | 2024-02-01T15:41:31Z | |
| dc.date.issued | 2014-03 | |
| dc.description.abstract | BackgroundHypertension self-management has been shown to improve systolic blood pressure (BP) control, but longer-term economic and clinical impacts are unknown. The purpose of this article is to examine clinical and economic outcomes 18 months after completion of a hypertension self-management trial.Methods and resultsThis study is a follow-up analysis of an 18-month, 4-arm, hypertension self-management trial of 591 veterans with hypertension who were randomized to usual care or 1 of 3 interventions. Clinic-derived systolic blood pressure obtained before, during, and after the trial were estimated using linear mixed models. Inpatient admissions, outpatient expenditures, and total expenditures were estimated using generalized estimating equations. The 3 telephone-based interventions were nurse-administered health behavior promotion, provider-administered medication adjustments based on hypertension treatment guidelines, or a combination of both. Intervention calls were triggered by home BP values transmitted via telemonitoring devices. Clinical and economic outcomes were examined 12 months before, 18 months during, and 18 months after trial completion. Compared with usual care, patients randomized to the combined arm had greater improvement in proportion of BP control during and after the 18-month trial and estimated proportion of BP control improved 18 months after trial completion for patients in the behavioral and medication management arms. Among the patients with inadequate baseline BP control, estimated mean systolic BP was significantly lower in the combined arm as compared with usual care during and after the 18-month trial. Utilization and expenditure trends were similar for patients in all 4 arms.ConclusionsBehavioral and medication management can generate systolic BP improvements that are sustained 18 months after trial completion.Clinical trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT00237692. | |
| dc.identifier | CIRCOUTCOMES.113.000309 | |
| dc.identifier.issn | 1941-7713 | |
| dc.identifier.issn | 1941-7705 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | Ovid Technologies (Wolters Kluwer Health) | |
| dc.relation.ispartof | Circulation. Cardiovascular quality and outcomes | |
| dc.relation.isversionof | 10.1161/circoutcomes.113.000309 | |
| dc.rights.uri | ||
| dc.subject | Humans | |
| dc.subject | Hypertension | |
| dc.subject | Antihypertensive Agents | |
| dc.subject | Blood Pressure Monitoring, Ambulatory | |
| dc.subject | Treatment Outcome | |
| dc.subject | Self Care | |
| dc.subject | Follow-Up Studies | |
| dc.subject | Telemedicine | |
| dc.subject | Time Factors | |
| dc.subject | Middle Aged | |
| dc.subject | Health Promotion | |
| dc.subject | Guideline Adherence | |
| dc.subject | United States | |
| dc.subject | Female | |
| dc.subject | Male | |
| dc.subject | Medication Adherence | |
| dc.title | Do the benefits of participation in a hypertension self-management trial persist after patients resume usual care? | |
| dc.type | Journal article | |
| duke.contributor.orcid | Maciejewski, Matthew L|0000-0003-1765-5938 | |
| duke.contributor.orcid | Bosworth, Hayden B|0000-0001-6188-9825 | |
| duke.contributor.orcid | Olsen, Maren K|0000-0002-9540-2103 | |
| duke.contributor.orcid | Smith, Valerie A|0000-0001-5170-9819 | |
| duke.contributor.orcid | Edelman, David|0000-0001-7112-6151 | |
| pubs.begin-page | 269 | |
| pubs.end-page | 275 | |
| pubs.issue | 2 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Biostatistics & Bioinformatics | |
| pubs.organisational-group | Family Medicine and Community Health | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Psychiatry & Behavioral Sciences | |
| pubs.organisational-group | Medicine, General Internal Medicine | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Duke Clinical Research Institute | |
| pubs.organisational-group | Institutes and Provost's Academic Units | |
| pubs.organisational-group | Center for the Study of Aging and Human Development | |
| pubs.organisational-group | Initiatives | |
| pubs.organisational-group | Duke Science & Society | |
| pubs.organisational-group | Population Health Sciences | |
| pubs.organisational-group | Duke Innovation & Entrepreneurship | |
| pubs.organisational-group | Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences | |
| pubs.organisational-group | Duke - Margolis Center For Health Policy | |
| pubs.organisational-group | Biostatistics & Bioinformatics, Division of Biostatistics | |
| pubs.publication-status | Published | |
| pubs.volume | 7 |
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