Electrocardiographic predictors of cardiovascular events in patients at high cardiovascular risk: a multicenter study.

Krittayaphong, Rungroj

Muenkaew, Muenpetch

Chiewvit, Polakit

Ratanasit, Nithima

Kaolawanich, Yodying

Phrommintikul, Arintaya

CORE Investigators

2019-10-01T13:27:01Z

2019-10-01T13:27:01Z

2019-08

2019-10-01T13:27:00Z

Background:There are limited data on the prevalence of electrocardiographic (ECG) abnormalities, and their value for predicting a major adverse cardiovascular event (MACE) in patients at high cardiovascular risk. This study aimed to determine the prevalence of ECG abnormalities in patients at high risk for cardiovascular events, and to identify ECG abnormalities that significantly predict MACE. Methods:Patients aged ≥ 45 years with established atherosclerotic disease (EAD) were consecutively enrolled from the outpatient clinics of the six participating hospitals during April 2011 to March 2014. The following data were collected: demographic data, cardiovascular risk factors, history of cardiovascular event, physical examination, ECG and medications. ECG was analyzed using Minnesota Code criteria. MACE included cardiovascular death, non-fatal myocardial infarction, and hospitalization due to unstable angina or heart failure. Results:A total of 2009 patients were included, 1048 patients (52.2%) had established EAD, and 961 patients (47.8%) had multiple risk factors (MRF). ECG abnormalities included atrial fibrillation (6.7%), premature ventricular contraction (5.4%), pathological Q-wave (Q/QS) (21.3%), T-wave inversion (20.0%), intraventricular ventricular conduction delay (IVCD) (7.3%), left ventricular hypertrophy (LVH) (12.2%), and AV block (12.5%). MACE occurred in 88 patients (4.4%). Independent predictors of MACE were chronic kidney disease, EAD, and the presence of atrial fibrillation, Q/QS, IVCD or LVH by ECG. Conclusions:A high prevalence of ECG abnormalities was found. The prevalence of ECG abnormalities was high even among those with risk factors without documented cardiovascular disease.

jgc-16-08-630

1671-5411

https://hdl.handle.net/10161/19351

eng

SCIENCE PRESS

Journal of geriatric cardiology : JGC

10.11909/j.issn.1671-5411.2019.08.004

CORE Investigators

Electrocardiographic predictors of cardiovascular events in patients at high cardiovascular risk: a multicenter study.

Journal article

630

638

8

School of Medicine

Duke

Medicine, Cardiology

Medicine

Clinical Science Departments

Published

16