Mullerian agenesis associated with in-utero thalidomide exposure: A case report
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2013-09-01
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Abstract
Thalidomide is a well-known teratogen, which is experiencing resurgence as new uses are identified. Exposure is classically associated with limb deformities, such as: dysmelia, phocomelia, preaxial hypoplasia and polydactyly, in addition to visceral anomalies that have been documented as well. We report a case of a 38 year-old nulligravid female, who was previously evaluated for primary amenorrhea, and given the presumptive false diagnosis of an imperforate hymen. On magnetic resonance imaging (MRI) exam, she was noted to have uterovaginal agenesis. The implications of thalidomide on women's health extend beyond external birth defects. Although, most commonly associated with limb deformities, there may also be gynecologic implications of in utero exposure. As this medication is increasingly used for various medical conditions, obstetricians/gynecologists need to remain aware of this potential mullerian teratogenic effect. © 2013 Production and hosting by Elsevier B.V. on behalf of Middle East Fertility Society.
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Dotters-Katz, S, LC Muasher and SJ Muasher (2013). Mullerian agenesis associated with in-utero thalidomide exposure: A case report. Middle East Fertility Society Journal, 18(3). pp. 214–216. 10.1016/j.mefs.2013.01.007 Retrieved from https://hdl.handle.net/10161/25033.
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Lisa Coates Muasher
Suheil Jamil Muasher
I currently hold the position of Director of Graduate Learning and Academic Development. I am responsible for the education of the second year residents rotating in REI and director of second year medical student rotation in REI. I give ten resident lectures per year covering all the CREOG educational requirements. I also conduct case based learning sessions for the medical students throughout the year (2 hours per week).
I conduct journal club sessions with the fellows in REI on a weekly basis. I conduct clinical research with the fellows that is translated into abstracts to the ASRM annual meeting and later, publications.
I am responsible for the departmental journal club conducted twice per year (5 articles presented by residents each time).
I overlook and co-moderate the departmental research day for the residents and fellows.
My time is divided into 50% clinical and 50% scholarly activities.
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