Mortality implications of mortality plateaus

dc.contributor.author

Missov, TI

dc.contributor.author

Vaupel, JW

dc.date.accessioned

2017-06-01T18:53:18Z

dc.date.available

2017-06-01T18:53:18Z

dc.date.issued

2015-01-01

dc.description.abstract

This article aims to describe in a unified framework all plateau-generating random effects models in terms of (i) plausible distributions for the hazard (baseline mortality) and the random effect (unobserved heterogeneity, frailty) as well as (ii) the impact of frailty on the baseline hazard. Mortality plateaus result from multiplicative (proportional) and additive hazards, but not from accelerated failure time models. Frailty can have any distribution with regularly-varying-at-0 density and the distribution of frailty among survivors to each subsequent age converges to a gamma distribution. In a multiplicative setting the baseline cumulative hazard can be represented as the inverse of the negative logarithm of any completely monotone function. If the plateau is reached, the only meaningful solution at the plateau is provided by the gamma-Gompertz model.

dc.identifier.issn

0036-1445

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https://hdl.handle.net/10161/14670

dc.publisher

Society for Industrial & Applied Mathematics (SIAM)

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SIAM Review

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10.1137/130912992

dc.title

Mortality implications of mortality plateaus

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Journal article

pubs.begin-page

61

pubs.end-page

70

pubs.issue

1

pubs.organisational-group

Center for Population Health & Aging

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Duke

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Duke Population Research Institute

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Sanford School of Public Policy

pubs.publication-status

Published

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57

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