How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria.
dc.contributor.author | Erickson, Harold P | |
dc.date.accessioned | 2018-04-01T14:40:12Z | |
dc.date.available | 2018-04-01T14:40:12Z | |
dc.date.issued | 2017-08 | |
dc.date.updated | 2018-04-01T14:40:10Z | |
dc.description.abstract | An important question for bacterial cell division is how the invaginating septum can overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it may not need to. Several studies in Gram-negative bacteria have shown that the periplasm is isoosmolar with the cytoplasm. Indirect evidence suggests that this is also true for Gram-positive bacteria. In this case the invagination of the septum takes place within the uniformly high osmotic pressure environment, and does not have to fight turgor pressure. A related question is how the V-shaped constriction of Gram-negative bacteria relates to the plate-like septum of Gram-positive bacteria. I collected evidence that Gram-negative bacteria have a latent capability of forming plate-like septa, and present a model in which septal division is the basic mechanism in both Gram-positive and Gram-negative bacteria. | |
dc.identifier.issn | 0265-9247 | |
dc.identifier.issn | 1521-1878 | |
dc.identifier.uri | ||
dc.language | eng | |
dc.publisher | Wiley | |
dc.relation.ispartof | BioEssays : news and reviews in molecular, cellular and developmental biology | |
dc.relation.isversionof | 10.1002/bies.201700045 | |
dc.subject | FtsZ | |
dc.subject | bacteria | |
dc.subject | cell division | |
dc.subject | cytokinesis | |
dc.subject | peptidoglycan | |
dc.subject | tubulin | |
dc.subject | turgor | |
dc.title | How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria. | |
dc.type | Journal article | |
pubs.issue | 8 | |
pubs.organisational-group | School of Medicine | |
pubs.organisational-group | Duke | |
pubs.organisational-group | Duke Cancer Institute | |
pubs.organisational-group | Institutes and Centers | |
pubs.organisational-group | Biochemistry | |
pubs.organisational-group | Basic Science Departments | |
pubs.organisational-group | Cell Biology | |
pubs.publication-status | Published | |
pubs.volume | 39 |
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