How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria.

dc.contributor.author

Erickson, Harold P

dc.date.accessioned

2018-04-01T14:40:12Z

dc.date.available

2018-04-01T14:40:12Z

dc.date.issued

2017-08

dc.date.updated

2018-04-01T14:40:10Z

dc.description.abstract

An important question for bacterial cell division is how the invaginating septum can overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it may not need to. Several studies in Gram-negative bacteria have shown that the periplasm is isoosmolar with the cytoplasm. Indirect evidence suggests that this is also true for Gram-positive bacteria. In this case the invagination of the septum takes place within the uniformly high osmotic pressure environment, and does not have to fight turgor pressure. A related question is how the V-shaped constriction of Gram-negative bacteria relates to the plate-like septum of Gram-positive bacteria. I collected evidence that Gram-negative bacteria have a latent capability of forming plate-like septa, and present a model in which septal division is the basic mechanism in both Gram-positive and Gram-negative bacteria.

dc.identifier.issn

0265-9247

dc.identifier.issn

1521-1878

dc.identifier.uri

https://hdl.handle.net/10161/16448

dc.language

eng

dc.publisher

Wiley

dc.relation.ispartof

BioEssays : news and reviews in molecular, cellular and developmental biology

dc.relation.isversionof

10.1002/bies.201700045

dc.subject

FtsZ

dc.subject

bacteria

dc.subject

cell division

dc.subject

cytokinesis

dc.subject

peptidoglycan

dc.subject

tubulin

dc.subject

turgor

dc.title

How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria.

dc.type

Journal article

pubs.issue

8

pubs.organisational-group

School of Medicine

pubs.organisational-group

Duke

pubs.organisational-group

Duke Cancer Institute

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Biochemistry

pubs.organisational-group

Basic Science Departments

pubs.organisational-group

Cell Biology

pubs.publication-status

Published

pubs.volume

39

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