Substance use disorders and comorbid Axis I and II psychiatric disorders among young psychiatric patients: findings from a large electronic health records database.

Wu, Li-Tzy

Gersing, Ken

Burchett, Bruce

Woody, George E

Blazer, Dan G

2020-02-03T05:42:21Z

2020-02-03T05:42:21Z

2011-11

2020-02-03T05:42:20Z

This study examined the prevalence of substance use disorders (SUDs) among psychiatric patients aged 2-17 years in an electronic health records database (N=11,457) and determined patterns of comorbid diagnoses among patients with a SUD to inform emerging comparative effectiveness research (CER) efforts. DSM-IV diagnoses of all inpatients and outpatients at a large university-based hospital and its associated psychiatric clinics were systematically captured between 2000 and 2010: SUD, anxiety (AD), mood (MD), conduct (CD), attention deficit/hyperactivity (ADHD), personality (PD), adjustment, eating, impulse-control, psychotic, learning, mental retardation, and relational disorders. The prevalence of SUD in the 2-12-year age group (n=6210) was 1.6% and increased to 25% in the 13-17-year age group (n=5247). Cannabis diagnosis was the most prevalent SUD, accounting for more than 80% of all SUD cases. Among patients with a SUD (n=1423), children aged 2-12 years (95%) and females (75-100%) showed high rates of comorbidities; blacks were more likely than whites to be diagnosed with CD, impulse-control, and psychotic diagnoses, while whites had elevated odds of having AD, ADHD, MD, PD, relational, and eating diagnoses. Patients with a SUD used more inpatient treatment than patients without a SUD (43% vs. 21%); children, females, and blacks had elevated odds of inpatient psychiatric treatment. Collectively, results add clinical evidence on treatment needs and diagnostic patterns for understudied diagnoses.

S0022-3956(11)00128-2

0022-3956

1879-1379

https://hdl.handle.net/10161/19990

eng

Elsevier BV

Journal of psychiatric research

10.1016/j.jpsychires.2011.06.012

Humans

Substance-Related Disorders

Prevalence

Risk Factors

Anxiety

Attention Deficit Disorder with Hyperactivity

Mood Disorders

Personality Disorders

Age Factors

Comorbidity

Sex Factors

Diagnostic and Statistical Manual of Mental Disorders

Adolescent

Child

Child, Preschool

Female

Male

Comparative Effectiveness Research

Electronic Health Records

Substance use disorders and comorbid Axis I and II psychiatric disorders among young psychiatric patients: findings from a large electronic health records database.

Journal article

Wu, Li-Tzy|0000-0002-5909-2259

1453

1462

11

School of Medicine

Duke

Center for Child and Family Policy

Sanford School of Public Policy

Duke Clinical Research Institute

Institutes and Centers

Duke Institute for Brain Sciences

University Institutes and Centers

Institutes and Provost's Academic Units

Psychiatry & Behavioral Sciences, Social and Community Psychiatry

Psychiatry & Behavioral Sciences

Clinical Science Departments

Medicine, General Internal Medicine

Medicine

Center for the Study of Aging and Human Development

Family Medicine and Community Health

Psychiatry & Behavioral Sciences, Geriatric Behavioral Health

Staff

Published

45