Advancing drug discovery for glomerulopathies using stem-cell-derived kidney models.
| dc.contributor.author | Barreto, Amanda D | |
| dc.contributor.author | Burt, Morgan A | |
| dc.contributor.author | Musah, Samira | |
| dc.date.accessioned | 2024-12-29T06:41:10Z | |
| dc.date.available | 2024-12-29T06:41:10Z | |
| dc.date.issued | 2023-04 | |
| dc.description.abstract | Chronic kidney disease (CKD) is an epidemic that affects millions worldwide. The glomerulus, a specialized unit of the nephron, is highly susceptible to injury. Human induced pluripotent stem cells (iPSCs) have emerged as an attractive resource for modeling kidney disease and therapeutic discovery. | |
| dc.identifier | S0165-6147(22)00258-9 | |
| dc.identifier.issn | 0165-6147 | |
| dc.identifier.issn | 1873-3735 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | Elsevier BV | |
| dc.relation.ispartof | Trends in pharmacological sciences | |
| dc.relation.isversionof | 10.1016/j.tips.2022.12.001 | |
| dc.rights.uri | ||
| dc.subject | Kidney | |
| dc.subject | Humans | |
| dc.subject | Kidney Diseases | |
| dc.subject | Cell Differentiation | |
| dc.subject | Drug Discovery | |
| dc.subject | Induced Pluripotent Stem Cells | |
| dc.title | Advancing drug discovery for glomerulopathies using stem-cell-derived kidney models. | |
| dc.type | Journal article | |
| pubs.begin-page | 204 | |
| pubs.end-page | 207 | |
| pubs.issue | 4 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | Pratt School of Engineering | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Cell Biology | |
| pubs.organisational-group | Biomedical Engineering | |
| pubs.organisational-group | Medicine | |
| pubs.organisational-group | Medicine, Nephrology | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.organisational-group | Duke Regeneration Center | |
| pubs.publication-status | Published | |
| pubs.volume | 44 |
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