Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): updated treatment recommendations for psoriatic arthritis 2021.

Coates, Laura C

Soriano, Enrique R

Corp, Nadia

Bertheussen, Heidi

Callis Duffin, Kristina

Campanholo, Cristiano B

Chau, Jeffrey

Eder, Lihi

Fernández-Ávila, Daniel G

FitzGerald, Oliver

Garg, Amit

Gladman, Dafna D

Goel, Niti

Helliwell, Philip S

Husni, M Elaine

Jadon, Deepak R

Katz, Arnon

Laheru, Dhruvkumar

Latella, John

Leung, Ying-Ying

Lindsay, Christine

Lubrano, Ennio

Mazzuoccolo, Luis Daniel

Mease, Philip J

O'Sullivan, Denis

Ogdie, Alexis

Olsder, Wendy

Palominos, Penelope Esther

Schick, Lori

Steinkoenig, Ingrid

de Wit, Maarten

van der Windt, DA

Kavanaugh, Arthur

GRAPPA Treatment Recommendations domain subcommittees

2022-12-01T17:23:59Z

2022-12-01T17:23:59Z

2022-08

2022-12-01T17:23:58Z

Since the second version of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations were published in 2015, therapeutic options for psoriatic arthritis (PsA) have advanced considerably. This work reviews the literature since the previous recommendations (data published 2013-2020, including conference presentations between 2017 and 2020) and reports high-quality, evidence-based, domain-focused recommendations for medication selection in PsA developed by GRAPPA clinicians and patient research partners. The overarching principles for the management of adults with PsA were updated by consensus. Principles considering biosimilars and tapering of therapy were added, and the research agenda was revised. Literature searches covered treatments for the key domains of PsA: peripheral arthritis, axial disease, enthesitis, dactylitis, and skin and nail psoriasis; additional searches were performed for PsA-related conditions (uveitis and inflammatory bowel disease) and comorbidities. Individual subcommittees used a GRADE-informed approach, taking into account the quality of evidence for therapies, to generate recommendations for each of these domains, which were incorporated into an overall schema. Choice of therapy for an individual should ideally address all disease domains active in that patient, supporting shared decision-making. As safety issues often affect potential therapeutic choices, additional consideration was given to relevant comorbidities. These GRAPPA treatment recommendations provide up-to-date, evidence-based guidance on PsA management for clinicians and people with PsA.

10.1038/s41584-022-00798-0

1759-4790

1759-4804

https://hdl.handle.net/10161/26279

eng

Springer Science and Business Media LLC

Nature reviews. Rheumatology

10.1038/s41584-022-00798-0

GRAPPA Treatment Recommendations domain subcommittees

Humans

Arthritis, Psoriatic

Psoriasis

Consensus

Comorbidity

Adult

Biosimilar Pharmaceuticals

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): updated treatment recommendations for psoriatic arthritis 2021.

Journal article

Goel, Niti|0000-0001-5869-5157

465

479

8

Duke

School of Medicine

Clinical Science Departments

Medicine

Medicine, Rheumatology and Immunology

Published

18