Assessment of age-related variation in cervical neuroforaminal dimensions.

Abstract

Radiographic parameters for diagnosing cervical neuroforaminal stenosis (CNFS) are not well described. To develop definitive criteria for diagnosis of CNFS, a standardized baseline of average neuroforaminal dimensions must first be established. Thus, the aim of this study was to: (1) use computed tomography (CT) of patients without neck pain or spinal pathology to establish mean cervical neuroforaminal dimensions (CNFD) across multiple age groups and (2) assess differences in CNFD by age. Cervical CT scans of 1,457 asymptomatic patients were reviewed to measure CNFD, defined as follows: axial width, craniocaudal height, and area. Patients were divided into four groups based on age: 18-35, 36-50, 51-64, and 65 + years. Statistical analyses were used to assess differences in CNFD according to age group.Mean overall CNFD for the 18-35 year-old cohort were 6.43 mm for width, 9.28 mm for height, and 58.85 mm2 for area. For the 36-50 year-old cohort, dimensions were 5.89 mm for width, 8.63 mm for height, and 52.78 mm2 for area. For the 51-64 year-old cohort, dimensions were 5.29 mm for width, 8.52 mm for height, and 48.93 mm2 for area. Finally, the 65 + year-old cohort had dimensions of 5.09 mm for width, 8.16 mm for height, and 45.91 mm2 for area. Significant differences in CNFD were observed between age groups, with dimensions decreasing in size from the younger to older age groups. In the studied population, CNFD decreased progressively with age. The results of our study may have utility in the diagnosis of CNFS.

Department

Description

Provenance

Subjects

Anatomy, CT, Cervical, Neuroforamina, Stenosis

Citation

Published Version (Please cite this version)

10.1016/j.jocn.2025.111095

Publication Info

Nguyen, Kai, Zachary Brandt, David Shin, Rohan Kubba, Ethan Vyhmeister, Jacob Razzouk, Christopher Shaffrey, Wayne Cheng, et al. (2025). Assessment of age-related variation in cervical neuroforaminal dimensions. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 134. p. 111095. 10.1016/j.jocn.2025.111095 Retrieved from https://hdl.handle.net/10161/32081.

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Scholars@Duke

Shaffrey

Christopher Ignatius Shaffrey

Professor of Orthopaedic Surgery

I have more than 25 years of experience treating patients of all ages with spinal disorders. I have had an interest in the management of spinal disorders since starting my medical education. I performed residencies in both orthopaedic surgery and neurosurgery to gain a comprehensive understanding of the entire range of spinal disorders. My goal has been to find innovative ways to manage the range of spinal conditions, straightforward to complex. I have a focus on managing patients with complex spinal disorders. My patient evaluation and management philosophy is to provide engaged, compassionate care that focuses on providing the simplest and least aggressive treatment option for a particular condition. In many cases, non-operative treatment options exist to improve a patient’s symptoms. I have been actively engaged in clinical research to find the best ways to manage spinal disorders in order to achieve better results with fewer complications.


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