Behavioural Genetics in the Postgenomics Era

Charney, E

2016-08-15T01:26:38Z

2014-01-01

There is growing evidence that the complexity of higher organisms does not correlate with the ‘complexity’ of the genome (the human genome contains fewer protein coding genes than corn, and many genes are preserved across species). Rather, complexity is associated with the complexity of the pathways and processes whereby the cell utilises the deoxyribonucleic acid molecule, and much else, in the process of phenotype formation. These pro- cesses include the activity of the epigenome, noncoding ribonucleic acids, alternative splicing and post-transla- tional modifications. Not accidentally, all of these pro- cesses appear to be of particular importance for the human brain, the most complex organ in nature. Because these processes can be highly environmentally reactive, they are a key to understanding behavioural plasticity and highlight the importance of the developmental process in explaining behavioural outcomes.

http://www.els.net/

https://hdl.handle.net/10161/12649

John Wiley & Sons

eLS

10.1002/9780470015902.a0025250

Behavioural Genetics in the Postgenomics Era

Journal article

http://www.els.net/

Duke

Duke Institute for Brain Sciences

Duke Science & Society

Initiatives

Institutes and Provost's Academic Units

Political Science

Sanford School of Public Policy

Trinity College of Arts & Sciences

University Institutes and Centers

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