Impact of Dominant Symptom on 12-Month Patient-Reported Outcomes for Patients Undergoing Lumbar Spine Surgery.

dc.contributor.author

Devin, Clinton J

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Asher, Anthony L

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Archer, Kristin R

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Goyal, Anshit

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Khan, Inamullah

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Kerezoudis, Panagiotis

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Alvi, Mohammed Ali

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Pennings, Jacquelyn S

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Karacay, Bernes

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Shaffrey, Christopher I

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Bisson, Erica F

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Knightly, John J

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Mummaneni, Praveen V

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Foley, Kevin T

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Bydon, Mohamad

dc.date.accessioned

2023-06-19T19:44:42Z

dc.date.available

2023-06-19T19:44:42Z

dc.date.issued

2020-10

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2023-06-19T19:44:42Z

dc.description.abstract

Background

The impact of symptom characteristics on outcomes of spine surgery remains elusive.

Objective

To determine the impact of symptom location, severity, and duration on outcomes following lumbar spine surgery.

Methods

We queried the Quality Outcomes Database (QOD) for patients undergoing elective lumbar spine surgery for lumbar degenerative spine disease. Multivariable regression was utilized to determine the impact of preoperative symptom characteristics (location, severity, and duration) on improvement in disability, quality of life, return to work, and patient satisfaction at 1 yr. Relative predictor importance was determined using an importance metric defined as Wald χ2 penalized by degrees of freedom.

Results

A total of 22 022 subjects were analyzed. On adjusted analysis, we found patients with predominant leg pain were more likely to be satisfied (P < .0001), achieve minimum clinically important difference (MCID) in Oswestry Disability Index (ODI) (P = .002), and return to work (P = .03) at 1 yr following surgery without significant difference in Euro-QoL-5D (EQ-5D) (P = .09) [ref = predominant back pain]. Patients with equal leg and back pain were more likely to be satisfied (P < .0001), but showed no significant difference in achieving MCID (P = .22) or return to work (P = .07). Baseline numeric rating scale-leg pain and symptom duration were most important predictors of achieving MCID and change in EQ-5D. Predominant symptom was not found to be an important determinant of return to work. Worker's compensation was found to be most important determinant of satisfaction and return to work.

Conclusion

Predominant symptom location is a significant determinant of functional outcomes following spine surgery. However, pain severity and duration have higher predictive importance. Return to work is more dependent on sociodemographic features as compared to symptom characteristics.
dc.identifier

5855653

dc.identifier.issn

0148-396X

dc.identifier.issn

1524-4040

dc.identifier.uri

https://hdl.handle.net/10161/28130

dc.language

eng

dc.publisher

Ovid Technologies (Wolters Kluwer Health)

dc.relation.ispartof

Neurosurgery

dc.relation.isversionof

10.1093/neuros/nyaa240

dc.subject

Lumbar Vertebrae

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Humans

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Low Back Pain

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Treatment Outcome

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Neurosurgical Procedures

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Quality of Life

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Databases, Factual

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Adult

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Aged

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Middle Aged

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Patient Satisfaction

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Female

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Male

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Intervertebral Disc Degeneration

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Symptom Assessment

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Patient Reported Outcome Measures

dc.title

Impact of Dominant Symptom on 12-Month Patient-Reported Outcomes for Patients Undergoing Lumbar Spine Surgery.

dc.type

Journal article

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

pubs.begin-page

1037

pubs.end-page

1045

pubs.issue

5

pubs.organisational-group

Duke

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School of Medicine

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Clinical Science Departments

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Orthopaedic Surgery

pubs.organisational-group

Neurosurgery

pubs.publication-status

Published

pubs.volume

87

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