Mating in wild yeast: delayed interest in sex after spore germination.
| dc.contributor.author | McClure, Allison W | |
| dc.contributor.author | Jacobs, Katherine C | |
| dc.contributor.author | Zyla, Trevin R | |
| dc.contributor.author | Lew, Daniel J | |
| dc.date.accessioned | 2022-03-01T15:16:10Z | |
| dc.date.available | 2022-03-01T15:16:10Z | |
| dc.date.issued | 2018-12 | |
| dc.date.updated | 2022-03-01T15:16:09Z | |
| dc.description.abstract | Studies of laboratory strains of Saccharomyces cerevisiae have uncovered signaling pathways involved in mating, including information-processing strategies to optimize decisions to mate or to bud. However, lab strains are heterothallic (unable to self-mate), while wild yeast are homothallic. And while mating of lab strains is studied using cycling haploid cells, mating of wild yeast is thought to involve germinating spores. Thus, it was unclear whether lab strategies would be appropriate in the wild. Here, we have investigated the behavior of several yeast strains derived from wild isolates. Following germination, these strains displayed large differences in their propensity to mate or to enter the cell cycle. The variable interest in sex following germination was correlated with differences in pheromone production, which were due to both cis- and trans-acting factors. Our findings suggest that yeast spores germinating in the wild may often enter the cell cycle and form microcolonies before engaging in mating. | |
| dc.identifier.issn | 1059-1524 | |
| dc.identifier.issn | 1939-4586 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | American Society for Cell Biology (ASCB) | |
| dc.relation.ispartof | Molecular biology of the cell | |
| dc.relation.isversionof | 10.1091/mbc.e18-08-0528 | |
| dc.subject | Saccharomyces cerevisiae | |
| dc.subject | Spores, Fungal | |
| dc.subject | Pheromones | |
| dc.subject | Cell Communication | |
| dc.subject | Cell Cycle | |
| dc.title | Mating in wild yeast: delayed interest in sex after spore germination. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Lew, Daniel J|0000-0001-7482-3585 | |
| pubs.begin-page | 3119 | |
| pubs.end-page | 3127 | |
| pubs.issue | 26 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Institutes and Centers | |
| pubs.organisational-group | Cell Biology | |
| pubs.organisational-group | Molecular Genetics and Microbiology | |
| pubs.organisational-group | Pharmacology & Cancer Biology | |
| pubs.organisational-group | Duke Cancer Institute | |
| pubs.publication-status | Published | |
| pubs.volume | 29 |
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