Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management.

dc.contributor.author

Zullig, Leah L

dc.contributor.author

Peterson, Eric D

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Shah, Bimal R

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Grambow, Steven C

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Oddone, Eugene Z

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McCant, Felicia

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Lindquist, Jennifer Hoff

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Bosworth, Hayden B

dc.date.accessioned

2023-11-12T17:38:49Z

dc.date.available

2023-11-12T17:38:49Z

dc.date.issued

2022-09

dc.date.updated

2023-11-12T17:38:48Z

dc.description.abstract

Objective

We evaluated the impact of a low intensity web-based and intensive nurse-administered intervention to reduce systolic blood pressure (SBP) among patients with prior MI.

Methods

Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE) was a three-arm trial. Patients were randomized to 1) post-MI education-only; 2) nurse-administered telephone program; or 3) web-based interactive tool. The study was conducted 2009-2013.

Results

Participants (n = 415) had a mean age of 61 years (standard deviation [SD], 11). Relative to the education-only group, the 12-month differential improvement in SBP was - 3.97 and - 3.27 mmHg for nurse-administered telephone and web-based groups, respectively. Neither were statistically significant. Post hoc exploratory subgroup analyses found participants who received a higher dose (>12 encounters) in the nurse-administered telephone intervention (n = 60; 46%) had an 8.8 mmHg (95% CI, 0.69, 16.89; p = 0.03) differential SBP improvement versus low dose (<11 encounters; n = 71; 54%). For the web-based intervention, those who had higher dose (n = 73; 53%; >1 web encounter) experienced a 2.3 mmHg (95% CI, -10.74, 6.14; p = 0.59) differential SBP improvement versus low dose (n = 65; 47%).

Conclusions

The main effects were not statistically significant.

Practical implications

Completing the full dose of the intervention may be essential to experience the intervention effect.

Clinical trial registration

The unique identifier is NCT00901277 (http://www.

Clinicaltrials

gov/ct2/show/NCT00901277?term=NCT00901277&rank=1).
dc.identifier

S0738-3991(22)00251-8

dc.identifier.issn

0738-3991

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1873-5134

dc.identifier.uri

https://hdl.handle.net/10161/29374

dc.language

eng

dc.publisher

Elsevier BV

dc.relation.ispartof

Patient education and counseling

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10.1016/j.pec.2022.05.011

dc.subject

Humans

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Myocardial Infarction

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Telemedicine

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Blood Pressure

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Middle Aged

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Patient Education as Topic

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Secondary Prevention

dc.title

Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management.

dc.type

Journal article

duke.contributor.orcid

Zullig, Leah L|0000-0002-6638-409X

duke.contributor.orcid

Grambow, Steven C|0000-0001-6037-3253

duke.contributor.orcid

Bosworth, Hayden B|0000-0001-6188-9825

pubs.begin-page

2962

pubs.end-page

2968

pubs.issue

9

pubs.organisational-group

Duke

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School of Medicine

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Basic Science Departments

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Clinical Science Departments

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Institutes and Centers

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Biostatistics & Bioinformatics

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Medicine

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Psychiatry & Behavioral Sciences

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Medicine, General Internal Medicine

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Duke Cancer Institute

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Duke Clinical Research Institute

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Institutes and Provost's Academic Units

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Center for the Study of Aging and Human Development

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Initiatives

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Duke Science & Society

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Population Health Sciences

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Duke Innovation & Entrepreneurship

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Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

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Duke - Margolis Center For Health Policy

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Biostatistics & Bioinformatics, Division of Biostatistics

pubs.publication-status

Published

pubs.volume

105

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