Inflammation, Atherosclerosis, and Psychological Factors

dc.contributor.author

Suarez, EC

dc.date.accessioned

2023-06-01T20:04:09Z

dc.date.available

2023-06-01T20:04:09Z

dc.date.issued

2022-01-01

dc.date.updated

2023-06-01T20:04:08Z

dc.description.abstract

Inflammation plays an important role in the etiology and pathophysiology of cardiovascular disease and its most common form, atherosclerosis. The present chapter provides the reader a short synopsis of the role of inflammation in the etiology of atherosclerotic cardiovascular disease (ACVD) and lists the most commonly used markers of inflammation and corresponding measurement techniques. With respect to behavioral and psychological factors, this review focuses on relevant studies that have examined the unique associations between inflammatory markers and psychological and behavioral factors associated with an increased risk of cardiovascular disease. These factors include major depressive disorder, severity of depressive symptoms, hostility, and anger. This review also describes an emerging body of evidence suggesting that combinations of psychological factors, and most prominently the combination of hostility and depressive symptoms, may be better predictors of inflammation than any single factor. The chapter concludes with a discussion of the bidirectional nature of the relationship between inflammation and psychological factors as well as the mechanisms potentially underlying these associations.

dc.identifier.isbn

9780387859590

dc.identifier.uri

https://hdl.handle.net/10161/27523

dc.publisher

Springer New York

dc.relation.isversionof

10.1007/978-0-387-85960-6_35

dc.title

Inflammation, Atherosclerosis, and Psychological Factors

dc.type

Book section

duke.contributor.orcid

Suarez, EC|0000-0003-3069-5846

pubs.begin-page

833

pubs.end-page

860

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Psychiatry & Behavioral Sciences

pubs.organisational-group

Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

pubs.publication-status

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