State of the psychometric methods: patient-reported outcome measure development and refinement using item response theory.

Stover, Angela M

McLeod, Lori D

Langer, Michelle M

Chen, Wen-Hung

Reeve, Bryce B

2019-09-03T12:42:56Z

2019-09-03T12:42:56Z

2019-07-30

2019-09-03T12:42:54Z

BACKGROUND:This paper is part of a series comparing different psychometric approaches to evaluate patient-reported outcome (PRO) measures using the same items and dataset. We provide an overview and example application to demonstrate 1) using item response theory (IRT) to identify poor and well performing items; 2) testing if items perform differently based on demographic characteristics (differential item functioning, DIF); and 3) balancing IRT and content validity considerations to select items for short forms. METHODS:Model fit, local dependence, and DIF were examined for 51 items initially considered for the Patient-Reported Outcomes Measurement Information System® (PROMIS®) Depression item bank. Samejima's graded response model was used to examine how well each item measured severity levels of depression and how well it distinguished between individuals with high and low levels of depression. Two short forms were constructed based on psychometric properties and consensus discussions with instrument developers, including psychometricians and content experts. Calibrations presented here are for didactic purposes and are not intended to replace official PROMIS parameters or to be used for research. RESULTS:Of the 51 depression items, 14 exhibited local dependence, 3 exhibited DIF for gender, and 9 exhibited misfit, and these items were removed from consideration for short forms. Short form 1 prioritized content, and thus items were chosen to meet DSM-V criteria rather than being discarded for lower discrimination parameters. Short form 2 prioritized well performing items, and thus fewer DSM-V criteria were satisfied. Short forms 1-2 performed similarly for model fit statistics, but short form 2 provided greater item precision. CONCLUSIONS:IRT is a family of flexible models providing item- and scale-level information, making it a powerful tool for scale construction and refinement. Strengths of IRT models include placing respondents and items on the same metric, testing DIF across demographic or clinical subgroups, and facilitating creation of targeted short forms. Limitations include large sample sizes to obtain stable item parameters, and necessary familiarity with measurement methods to interpret results. Combining psychometric data with stakeholder input (including people with lived experiences of the health condition and clinicians) is highly recommended for scale development and evaluation.

10.1186/s41687-019-0130-5

2509-8020

2509-8020

https://hdl.handle.net/10161/19282

eng

Springer Science and Business Media LLC

Journal of patient-reported outcomes

10.1186/s41687-019-0130-5

Item response theory

Measurement

PROMIS®

Scale construction

Scale evaluation

State of the psychometric methods: patient-reported outcome measure development and refinement using item response theory.

Journal article

Reeve, Bryce B|0000-0002-6709-8714

50

1

School of Medicine

Duke

Duke Cancer Institute

Institutes and Centers

Duke Clinical Research Institute

Population Health Sciences

Basic Science Departments

Published

3