Lipid emulsions in parenteral nutrition: does it matter?
| dc.contributor.author | Haines, Krista | |
| dc.contributor.author | Grisel, Braylee | |
| dc.contributor.author | Gorenshtein, Laura | |
| dc.contributor.author | Wischmeyer, Paul E | |
| dc.date.accessioned | 2023-07-04T04:03:01Z | |
| dc.date.available | 2023-07-04T04:03:01Z | |
| dc.date.issued | 2023-06 | |
| dc.date.updated | 2023-07-04T04:02:56Z | |
| dc.description.abstract | Purpose of reviewRecently, clinicians have shown interest in switching patients to nonsoybean-based intravenous lipid emulsion (ILE) formulas for parental nutrition (PN) due to adverse outcomes related to high Omega-6 content in soybean oil (SO) ILE's. This review summarizes recent literature on improved clinical outcomes with new Omega-6 lipid-sparing ILE's in PN management.Recent findingsAlthough there is a paucity of large-scale studies directly comparing Omega-6 lipid sparing ILE's with SO-based lipid emulsion use in PN in ICU patients, there is strong translational and meta-analysis evidence to suggest that lipid formulations containing fish oil (FO) and/or olive oil (OO) have favorable effects on immune function and improve clinical outcomes in ICU populations.SummaryMore research is needed to directly compare omega-6-sparing PN formulas with FO and/or OO versus traditional SO ILE's. However, current evidence is promising for improved outcomes using newer ILE's including reduced infections, shorter lengths of stay, and reduced costs. | |
| dc.identifier | 00075198-990000000-00083 | |
| dc.identifier.issn | 1070-5295 | |
| dc.identifier.issn | 1531-7072 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.publisher | Ovid Technologies (Wolters Kluwer Health) | |
| dc.relation.ispartof | Current opinion in critical care | |
| dc.relation.isversionof | 10.1097/mcc.0000000000001058 | |
| dc.title | Lipid emulsions in parenteral nutrition: does it matter? | |
| dc.type | Journal article | |
| duke.contributor.orcid | Haines, Krista|0000-0002-2056-1820 | |
| duke.contributor.orcid | Wischmeyer, Paul E|0000-0002-3369-7911 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Clinical Science Departments | |
| pubs.organisational-group | Anesthesiology | |
| pubs.organisational-group | Anesthesiology, Critical Care Medicine | |
| pubs.organisational-group | Surgery | |
| pubs.organisational-group | Trauma, Acute, and Critical Care Surgery | |
| pubs.publication-status | Published | |
| pubs.volume | Publish Ahead of Print |
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