Frequency of Occult High-Grade Squamous Intraepithelial Neoplasia and Invasive Cancer within Anal Condylomata in Men Who Have Sex with Men

Abstract

Human papillomavirus causes anal condylomata, high-grade anal intraepithelial neoplasia, and anal squamous cell cancer. We found high-grade intraepithelial neoplasia or squamous cell cancer in 75 (47%) of 159 HIV-seropositive men who have sex with men (MSM) and in 42 (26%) of 160 HIV-seronegative MSM with anal condylomata meriting surgery (P < .001, determined by use of the X-2 test). Anal condylomata in MSM often harbor high-grade intraepithelial neoplasia and squamous cell cancer.

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Citation

Schlecht,Hans P.;Fugelso,Dana K.;Murphy,Ryan K.;Wagner,Katiri T.;Doweiko,John P.;Proper,JoAnn;Dezube,Bruce J.;Panther,Lori A.. 2010. Frequency of Occult High-Grade Squamous Intraepithelial Neoplasia and Invasive Cancer within Anal Condylomata in Men Who Have Sex with Men. Clinical Infectious Diseases 51(1): 107-110.

Published Version (Please cite this version)

10.1086/653426


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