Nonmedical Opioid Pain Relievers and All-Cause Mortality: A 27-Year Follow-Up From the Epidemiologic Catchment Area Study.

dc.contributor.author

Cottler, Linda B

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Hu, Hui

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Smallwood, Bryan A

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Anthony, James C

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Wu, Li-Tzy

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Eaton, William W

dc.date.accessioned

2020-02-03T04:23:59Z

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2020-02-03T04:23:59Z

dc.date.issued

2016-03

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2020-02-03T04:23:58Z

dc.description.abstract

We investigated whether nonmedical opioid pain reliever use is associated with higher mortality in the general US population.We assessed the history of nonmedical opioid pain reliever use among 9985 people interviewed at baseline of the Epidemiologic Catchment Area Program initiated in 1981 to 1983 in Baltimore, Maryland; St. Louis, Missouri; and Durham, North Carolina. We linked the data with the National Death Index through 2007.Nonmedical opioid pain reliever use was 1.4%. Compared with no nonmedical drug use, mortality was increased for nonmedical opioid pain reliever use (hazard ratio [HR] = 1.60; 95% confidence interval [CI] = 1.01, 2.53) or nonmedical use of other drugs (HR = 1.31; 95% CI = 1.07, 1.62). Mortality was also higher for males and for those beginning nonmedical opioid pain reliever use before aged 15 years.A history of nonmedical opioid pain reliever use was associated with increased mortality, in particular for males and early onset users.

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0090-0036

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1541-0048

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https://hdl.handle.net/10161/19947

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eng

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American Public Health Association

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American journal of public health

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10.2105/ajph.2015.302961

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Humans

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Alcoholism

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Opioid-Related Disorders

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Analgesics, Opioid

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Mortality

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Smoking

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Age Distribution

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Sex Distribution

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Socioeconomic Factors

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Adolescent

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Adult

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Aged

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Middle Aged

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United States

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Female

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Male

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Young Adult

dc.title

Nonmedical Opioid Pain Relievers and All-Cause Mortality: A 27-Year Follow-Up From the Epidemiologic Catchment Area Study.

dc.type

Journal article

duke.contributor.orcid

Wu, Li-Tzy|0000-0002-5909-2259

pubs.begin-page

509

pubs.end-page

516

pubs.issue

3

pubs.organisational-group

School of Medicine

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Duke

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Center for Child and Family Policy

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Sanford School of Public Policy

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Duke Clinical Research Institute

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Institutes and Centers

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Duke Institute for Brain Sciences

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University Institutes and Centers

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Institutes and Provost's Academic Units

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Psychiatry & Behavioral Sciences, Social and Community Psychiatry

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Psychiatry & Behavioral Sciences

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Clinical Science Departments

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Medicine, General Internal Medicine

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Medicine

pubs.publication-status

Published

pubs.volume

106

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