Patient-reported medication adherence barriers among patients with cardiovascular risk factors.

dc.contributor.author

Zullig, Leah L

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Stechuchak, Karen M

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Goldstein, Karen M

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Olsen, Maren K

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McCant, Felicia M

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Danus, Susanne

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Crowley, Matthew J

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Oddone, Eugene Z

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Bosworth, Hayden B

dc.date.accessioned

2024-02-01T15:15:32Z

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2024-02-01T15:15:32Z

dc.date.issued

2015-06

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Background

Many patients experience barriers that make it difficult to take cardiovascular disease (CVD)-related medications as prescribed. The Cardiovascular Intervention Improvement Telemedicine Study (CITIES) was a tailored behavioral pharmacist-administered and telephone-based intervention for reducing CVD risk.

Objectives

To (a) describe patient-reported barriers to taking their medication as prescribed and (b) evaluate patient-level characteristics associated with reporting medication barriers.

Methods

We recruited patients receiving care at primary care clinics affiliated with Durham Veterans Affairs Medical Center. Eligible patients were diagnosed with hypertension and/or hyperlipidemia that were poorly controlled (blood pressure of > 150/100 mmHg and/or low-density lipoprotein value > 130 mg/dL). At the time of enrollment, patients completed an interview with 7 questions derived from a validated medication barriers measure. Patient characteristics and individual medication treatment barriers are described. Multivariable linear regression was used to examine the association between a medication barrier score and patient characteristics.

Results

Most patients (n = 428) were married or living with their partners (57%) and were men (85%) who were diagnosed with hypertension and hyperlipidemia (64%). The most commonly reported barriers were having too much medication to take (31%) and forgetting whether medication was taken at a particular time (24%). In adjusted analysis, those who were not employed (1.32, 95% CI = 0.50-2.14) or did not have someone to help with tasks, if needed (1.66, 95% CI = 0.42-2.89), reported higher medication barrier scores. Compared with those diagnosed with hypertension and hyperlipidemia, those with only hypertension (0.91, 95% CI = 0.04-1.79) reported higher medication barrier scores.

Conclusions

Barriers to medication adherence are common. Evaluating and addressing barriers may increase medication adherence.
dc.identifier

2015(21)6: 479-485

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2376-0540

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2376-1032

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https://hdl.handle.net/10161/29986

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eng

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Academy of Managed Care Pharmacy

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Journal of managed care & specialty pharmacy

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10.18553/jmcp.2015.21.6.479

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https://creativecommons.org/licenses/by-nc/4.0

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Humans

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Cardiovascular Diseases

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Hypertension

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Linear Models

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Risk Factors

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Telephone

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Aged

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Middle Aged

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Pharmacists

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Pharmacy Service, Hospital

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Hospitals, Veterans

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Primary Health Care

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Female

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Male

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Hyperlipidemias

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Medication Adherence

dc.title

Patient-reported medication adherence barriers among patients with cardiovascular risk factors.

dc.type

Journal article

duke.contributor.orcid

Zullig, Leah L|0000-0002-6638-409X

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Goldstein, Karen M|0000-0003-4419-5869

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Olsen, Maren K|0000-0002-9540-2103

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Crowley, Matthew J|0000-0002-6205-4536

duke.contributor.orcid

Bosworth, Hayden B|0000-0001-6188-9825

pubs.begin-page

479

pubs.end-page

485

pubs.issue

6

pubs.organisational-group

Duke

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School of Medicine

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Basic Science Departments

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Clinical Science Departments

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Institutes and Centers

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Biostatistics & Bioinformatics

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Medicine

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Psychiatry & Behavioral Sciences

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Medicine, Endocrinology, Metabolism, and Nutrition

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Medicine, General Internal Medicine

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Duke Cancer Institute

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Duke Clinical Research Institute

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Institutes and Provost's Academic Units

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Center for the Study of Aging and Human Development

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Initiatives

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Duke Science & Society

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Population Health Sciences

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Duke Innovation & Entrepreneurship

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Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

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Duke - Margolis Center For Health Policy

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Biostatistics & Bioinformatics, Division of Biostatistics

pubs.publication-status

Published

pubs.volume

21

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