High-Impact Chronic Pain Transition in Lumbar Surgery Recipients.

dc.contributor.author

Cook, Chad E

dc.contributor.author

George, Steven Z

dc.contributor.author

Lentz, Trevor

dc.contributor.author

Park, Christine

dc.contributor.author

Shaffrey, Christopher I

dc.contributor.author

Goodwin, C Rory

dc.contributor.author

Than, Khoi D

dc.contributor.author

Gottfried, Oren N

dc.date.accessioned

2023-06-15T16:27:53Z

dc.date.available

2023-06-15T16:27:53Z

dc.date.issued

2023-03

dc.date.updated

2023-06-15T16:27:52Z

dc.description.abstract

Objective

High-impact chronic pain (HICP) is a term that characterizes the presence of a severe and troubling pain-related condition. To date, the prevalence of HICP in lumbar spine surgery recipients and their HICP transitions from before to after surgery are unexplored. The purpose was to define HICP prevalence, transition types, and outcomes in lumbar spine surgery recipients and to identify predictors of HICP outcomes.

Methods

In total, 43,536 lumbar surgery recipients were evaluated for HICP transition. Lumbar spine surgery recipients were categorized as having HICP preoperatively and at 3 months after surgery if they exhibited chronic and severe pain and at least one major activity limitation. Four HICP transition groups (Stable Low Pain, Transition from HICP, Transition to HICP, and Stable High Pain) were categorized and evaluated for outcomes. Multivariate multinomial modeling was used to predict HICP transition categorization.

Results

In this sample, 15.1% of individuals exhibited HICP preoperatively; this value declined to 5.1% at 3 months after surgery. Those with HICP at baseline and 3 months had more comorbidities and worse overall outcomes. Biological, psychological, and social factors predicted HICP transition or Stable High Pain; some of the strongest involved social factors of 2 or more to transition to HICP (OR = 1.43; 95% CI = 1.21-1.68), and baseline report of pain/disability (OR = 3.84; 95% CI = 3.20-4.61) and psychological comorbidity (OR = 1.78; 95% CI = 1.48-2.12) to Stable Stable High Pain.

Conclusion

The percentage of individuals with HICP preoperatively (15.1%) was low, which further diminished over a 3-month period (5.1%). Postoperative HICP groups had higher levels of comorbidities and worse baseline outcomes scores. Transition to and maintenance of HICP status was predicted by biological, psychological, and social factors.
dc.identifier

6749596

dc.identifier.issn

1526-2375

dc.identifier.issn

1526-4637

dc.identifier.uri

https://hdl.handle.net/10161/27970

dc.language

eng

dc.publisher

Oxford University Press (OUP)

dc.relation.ispartof

Pain medicine (Malden, Mass.)

dc.relation.isversionof

10.1093/pm/pnac150

dc.subject

Lumbosacral Region

dc.subject

Lumbar Vertebrae

dc.subject

Humans

dc.subject

Pain, Postoperative

dc.subject

Treatment Outcome

dc.subject

Comorbidity

dc.subject

Disabled Persons

dc.subject

Chronic Pain

dc.title

High-Impact Chronic Pain Transition in Lumbar Surgery Recipients.

dc.type

Journal article

duke.contributor.orcid

Cook, Chad E|0000-0001-8622-8361|0000-0002-5045-3281

duke.contributor.orcid

George, Steven Z|0000-0003-4988-9421

duke.contributor.orcid

Lentz, Trevor|0000-0002-4286-0733

duke.contributor.orcid

Shaffrey, Christopher I|0000-0001-9760-8386

duke.contributor.orcid

Goodwin, C Rory|0000-0002-6540-2751

pubs.begin-page

258

pubs.end-page

268

pubs.issue

3

pubs.organisational-group

Duke

pubs.organisational-group

School of Medicine

pubs.organisational-group

Basic Science Departments

pubs.organisational-group

Clinical Science Departments

pubs.organisational-group

Institutes and Centers

pubs.organisational-group

Orthopaedic Surgery

pubs.organisational-group

Radiation Oncology

pubs.organisational-group

Duke Cancer Institute

pubs.organisational-group

Duke Clinical Research Institute

pubs.organisational-group

Institutes and Provost's Academic Units

pubs.organisational-group

Initiatives

pubs.organisational-group

Orthopaedic Surgery, Physical Therapy

pubs.organisational-group

Neurosurgery

pubs.organisational-group

Population Health Sciences

pubs.organisational-group

Duke - Margolis Center For Health Policy

pubs.publication-status

Published

pubs.volume

24

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
00007632-900000000-93232.pdf
Size:
1.19 MB
Format:
Adobe Portable Document Format