Risk of spontaneous preterm birth in relation to maternal depressive, anxiety, and stress symptoms.
| dc.contributor.author | Sanchez, Sixto E | |
| dc.contributor.author | Puente, Gabriella C | |
| dc.contributor.author | Atencio, Guillermo | |
| dc.contributor.author | Qiu, Chungfang | |
| dc.contributor.author | Yanez, David | |
| dc.contributor.author | Gelaye, Bizu | |
| dc.contributor.author | Williams, Michelle A | |
| dc.date.accessioned | 2024-06-11T13:49:31Z | |
| dc.date.available | 2024-06-11T13:49:31Z | |
| dc.date.issued | 2013-01 | |
| dc.description.abstract | ObjectiveTo examine the risk of preterm birth (PTB) in relation to maternal psychiatric symptoms during pregnancy in Peruvian women.Study designThis case-control study included 479 PTB cases and 480 term controls. In-person interviews were conducted to assess women's depressive, anxiety, and stress symptoms using the Patient Health Questionnaire (PHQ-9) and the Depression Anxiety Stress Scales (DASS-21). Multivariable logistic regression procedures were used to estimate adjusted odds ratios (aORs) and 95% confidence intervals (CIs).ResultsCompared with women reporting no or minimal depressive symptoms, the aOR (95% CI) for PTB associated with consecutive severity of depressive symptoms based on the PHQ-9 assessment method were as follows: mild, 2.22 (95% CI 1.64-3.00) and moderate-severe, 3.67 (95% CI 2.09-6.46). The corresponding aORs for normal, mild, and moderate-severe depressive symptoms based on the DASS-21 assessment were 1.00 (reference), 3.82 (95% CI 1.90-7.66), and 2.90 (95% CI 1.66-5.04), respectively. A positive gradient was observed for the odds of PTB with severity of anxiety (Ptrend < 0.001) and stress symptoms (Ptrend < 0.001).ConclusionThe odds of PTB increased in pregnant Peruvian women with psychiatric symptoms. Efforts to screen and treat affected women may modify risks of PTB and possibly other associated disorders. | |
| dc.identifier.issn | 0024-7758 | |
| dc.identifier.issn | 1943-3565 | |
| dc.identifier.uri | ||
| dc.language | eng | |
| dc.relation.ispartof | The Journal of reproductive medicine | |
| dc.rights.uri | ||
| dc.subject | Humans | |
| dc.subject | Premature Birth | |
| dc.subject | Confidence Intervals | |
| dc.subject | Logistic Models | |
| dc.subject | Odds Ratio | |
| dc.subject | Risk Factors | |
| dc.subject | Case-Control Studies | |
| dc.subject | Depression | |
| dc.subject | Stress, Psychological | |
| dc.subject | Anxiety | |
| dc.subject | Psychiatric Status Rating Scales | |
| dc.subject | Pregnancy | |
| dc.subject | Adult | |
| dc.subject | Female | |
| dc.subject | Young Adult | |
| dc.subject | Surveys and Questionnaires | |
| dc.title | Risk of spontaneous preterm birth in relation to maternal depressive, anxiety, and stress symptoms. | |
| dc.type | Journal article | |
| duke.contributor.orcid | Yanez, David|0000-0002-2501-5028 | |
| pubs.begin-page | 25 | |
| pubs.end-page | 33 | |
| pubs.issue | 1-2 | |
| pubs.organisational-group | Duke | |
| pubs.organisational-group | School of Medicine | |
| pubs.organisational-group | Basic Science Departments | |
| pubs.organisational-group | Biostatistics & Bioinformatics | |
| pubs.organisational-group | Biostatistics & Bioinformatics, Division of Biostatistics | |
| pubs.publication-status | Published | |
| pubs.volume | 58 |
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